The impact of antibiotic therapy on the diagnosis of healthcare-associated ventriculitis and meningitis (HCAVM) is unknown. Antibiotics were administered before obtaining cerebrospinal fluid (CSF) in 217 out of 326 (66%) patients with HCAVM, and they impacted the sensitivity of the cerebrospinal fluid Gram stain and culture ( ≤ .004).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422431PMC
http://dx.doi.org/10.1093/ofid/ofz050DOI Listing

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