BACKGROUND Strongyloides stercoralis is an intestinal helminth. Parasitism is caused by penetration of the larvae through the skin. It is endemic in tropical and subtropical regions of the world and in the United States occurs in the southeastern region. It has a tendency to remain dormant or progress to a state of hyper-infection during immunosuppression. CASE REPORT We present the case of a 70-year-old Nigerian who developed fatal ARDS secondary to Strongyloides infection after been treated with steroids for treatment of autoimmune necrotizing myopathy. Despite adequate management with mechanical ventilation and appropriate antifungal therapy, the patient died on day 19 of hospitalization. CONCLUSIONS S. stercoralis is known to affect every organ in the body. ARDS is often an overlooked complication of Strongyloides hyper-infection, which is often deadly. Immediate diagnosis and treatment are important for patient survival.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439959 | PMC |
| http://dx.doi.org/10.12659/AJCR.914640 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Genetic Diversity of with Attention to Clinical Features in Patients Originated from Three Endemic Provinces in the North and South of Iran.
Iran J Parasitol
January 2024
Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Background: is one of the neglected tropical diseases. We aimed to verify the genetic diversity of with attention to clinical features of the infection in patients using the 1 gene and DNA sequencing.
Methods: Using parasitological methods, was isolated from stool samples of patients who had been referred to Tehran University of Medical Sciences, Tehran, Iran.
Strongyloides stercoralis infection in the UK: A systematic review and meta-analysis of published cases.
Clin Med (Lond)
July 2024
Antimicrobial Pharmacodynamics and Therapeutics Group, Institute of Systems, Molecular and Integrative Biology, William Henry Duncan Building, 6 West Derby Street, University of Liverpool, Liverpool L7 8TX, UK. Electronic address:
Article Synopsis
- Strongyloidiasis is a parasitic infection that often shows no symptoms but can be severe in those with weakened immune systems, leading to a dangerous 'hyper-infection' status.
- A review of 1,308 cases in the UK found that 27.7% were asymptomatic, with the highest risk groups being migrants, travellers, and military personnel.
- Common symptoms included abdominal pain (32.1%), skin rashes (38.4%), and diarrhea (12.6%), suggesting that screening should be proactive for individuals showing any symptoms in at-risk categories.
hyper-infection in a lung transplant recipient: Case report and review of the literature.
J Assoc Med Microbiol Infect Dis Can
June 2022
Multi-Organ Transplant Program, Division of Infectious Diseases, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Case Presentation: A 63-year-old man with a left single lung transplant for end-stage combined restrictive and obstructive lung disease developed persistent pulmonary infiltrates and recurrent gram-negative bacteremia post-transplant. Bronchoalveolar lavage fluid revealed a nematode on Papanicolau staining compatible with larvae on day 50 post-transplant. Although serology performed post-transplant was negative, a retrospective review of the medical record revealed marked peripheral blood eosinophilia on several occasions before transplantation.
View Article and Find Full Text PDFHyperinfection with presenting as acute abdomen in a patient on corticosteroid therapy: A case report.
Indian J Pathol Microbiol
January 2022
Department of Pathology, Dr. D.Y. Patil Medical College and Hospital, Sector 5, Nerul, Navi Mumbai, Maharashtra, India.
Infection with Strongyloides stercoralis, a human pathogenic roundworm, is common in tropical countries like India. Owing to its variable clinical presentation and irregular larval output in stool, it often remains neglected and underdiagnosed. Signs and symptoms are largely dependent on the immune status of the infected individual.
View Article and Find Full Text PDFStrongyloides Hyper-Infection Syndrome and Ciliocytophthoria Mimicking .
Eur J Case Rep Intern Med
July 2021
WVU School of Medicine, Department of Infectious Diseases, Morgantown, WV, USA.
Unlabelled: Ciliocytophthoria is a phenomenon where degenerated cells in infections or malignancy can present as ciliated cells on microscopy and so may be confused with ciliated parasitic infection. We present an interesting case of recurrent shortness of breath, misdiagnosed as chronic obstructive pulmonary disease exacerbations leading to unnecessary exposure to antimicrobials and steroids. The case was diagnosed as hyper-infection syndrome.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!