AI Article Synopsis
- - An 83-year-old man with bleeding gums was thought to have a benign tumor in his upper gingiva, leading to surgical removal of the lesion.
- - The removed tissue was analyzed and found to contain ulcerative granuloma and bacterial colonies, indicating an unusual case of orofacial actinomycosis.
- - DNA testing (PCR) confirmed the presence of actinomycosis, which helped in accurately diagnosing the condition as a pyogenic granuloma associated with the infection.
Article Abstract
Peculiar findings of orofacial actinomycosis mimicking the clinical appearance of a tumor of the upper gingiva are reported. An 83-year-old man with bleeding of the gingiva visited our hospital. The clinical diagnosis was a benign gingival tumor, and the lesion was surgically removed. Histologically, the excised specimens showed an ulcerative granuloma lesion covered by bacterial colonies consisting of club-shaped filaments. DNA samples were extracted from paraffin sections and examined by polymerase chain reaction (PCR) for species. The PCR products examined by direct DNA sequencing demonstrated the presence of . Finally, a pathological diagnosis was made of a pyogenic granuloma associated with actinomycosis. The PCR method aided the early and exact diagnosis of the paraffin-embedded sample of oral mucosal infectious diseases including actinomycosis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388859 | PMC |
| http://dx.doi.org/10.1016/j.jds.2012.09.026 | DOI Listing |
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