Alveolar soft-part sarcoma of the masseter and mandibular ramus: Report of a case and review of the literature.

J Dent Sci

Oral Pathology Department, Faculty of Dentistry, Universidad Andrés Bello, Viña del Mar, Chile.

Published: March 2018

AI Article Synopsis

  • Alveolar soft-part sarcomas are unique soft-tissue tumors with unclear origins, commonly found in the head and neck regions, particularly in the orbit and tongue.
  • A case study highlights a 28-year-old female with a sarcoma in her left masseter, presenting with chronic pain and numbness in her left lower lip.
  • Imaging revealed a distinct mass, and a biopsy confirmed the tumor's characteristics, showing positive markers for myoglobin, actin, and desmin, which are important for diagnosis.

Article Abstract

Alveolar soft-part sarcomas are clinically and morphologically distinct soft-tissue sarcomas, with an unknown histogenesis. When the tumors affect the region of the head and neck, they are often located in the orbit and tongue. We report a case of an alveolar soft-part sarcoma in the left masseter of a 28-year-old female. The patient had chronic pain and paresthesia of her left lower lip. Panoramic radiography and computed tomography showed a well-delimited radiolucent mass in the left ramus. An incisional biopsy was performed, and the sample submitted for histopathological study. The tumor showed positive periodic acid-Schiff diastase-resistant granules. Immunohistochemically, the tumor cells were diffusely positive for myoglobin, and focally positive for actin and desmin.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388804PMC
http://dx.doi.org/10.1016/j.jds.2013.02.032DOI Listing

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