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Microvascular blood flow ultrasound imaging with microbubble-based H-Scan technology.
Med Biol Eng Comput
January 2025
Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Science, Suzhou, 215613, China.
Ultrasound blood flow imaging plays a crucial role in the diagnosis of cardiovascular and cerebrovascular diseases. Conventional ultrafast ultrasound plane-wave imaging techniques have limited capabilities in microvascular imaging. To enhance the quality of blood flow imaging, this study proposes a microbubble-based H-Scan ultrasound imaging technique.
View Article and Find Full Text PDFComplete blood counts as potential risk factors of early dissemination to liver and lungs in resected colorectal cancer: a retrospective cohort study.
Int J Colorectal Dis
January 2025
Department of Pathomorphology, Medical University of Gdańsk, Gdańsk, Poland.
Purpose: Liver and lung metastases demonstrate distinct biological, particularly immunological, characteristics. We investigated whether preoperative complete blood count (CBC) parameters, which may reflect the immune system condition, predict early dissemination to the liver and lungs in colorectal cancer (CRC).
Methods: In this retrospective single-centre study, we included 268 resected CRC cases with complete 2-year follow-up and analysed preoperative CBC for association with early liver or lung metastasis development.
Detecting CYP2C19 genes through an integrated CRISPR/Cas13a-assisted system.
Anal Methods
January 2025
School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
CYP2C19 gene single nucleotide polymorphisms (SNPs) should be considered in the clinical use of clopidogrel as they have important guiding value for predicting the risk of bleeding and thrombosis after clopidogrel treatment. The CRISPR/Cas system is increasingly used for SNP detection owing to its single-nucleotide mismatch specificity. Simultaneous detection of multiple SNPs for rapid identification of the CYP2C19 genotype is important, but there is no method to detect a wide variety of CYP2C19 SNPs.
View Article and Find Full Text PDFAdvancing Soft Robot Proprioception Through 6D Strain Sensors Embedding.
Soft Robot
January 2025
Department of Mechanical and Nuclear Engineering, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.
Soft robots and bioinspired systems have revolutionized robot design by incorporating flexibility and deformable materials inspired by nature's ingenious designs. Similar to many robotic applications, sensing and perception are paramount to enable soft robots to adeptly navigate the unpredictable real world, ensuring safe interactions with both humans and the environment. Despite recent progress, soft robot sensorization still faces significant challenges due to the virtual infinite degrees of freedom of the system and the need for efficient computational models capable of estimating valuable information from sensor data.
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