To evaluate and compare the outcomes of pregnancies with prenatally detected gastroschisis and omphalocele. We retrospectively evaluated prenatally detected gastroschisis and omphalocele cases. Cases were compared in terms of maternal demographic and clinical characteristics as well as pregnancy and neonatal outcomes. This study consisted of 17 gastroschisis and 30 omphalocele cases. Only one case with gastroschisis was terminated due to additional severe limb deformities. Seventeen out of 30 cases of omphalocele were terminated for various reasons (56.7%). All patients with gastroschisis had surgical repair, while 8 out of 13 omphalocele cases had surgery. One patient with an omphalocele died after surgery due to sepsis. Six cases of gastroschisis also died in the neonatal period due to various reasons (6/16, 37.5%). Additional genetic disorders are more frequent in those with omphalocele cases, and they are more frequently terminated during gestation that the gastroschisis fetuses.
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Article Synopsis
- Gastroschisis and omphalocele are common abdominal wall defects in newborns that can lead to serious health issues, and managing them effectively remains a challenge despite surgical advancements.!
- The retrospective study at Tikur Anbessa Specialized Hospital examined 50 neonates with these defects between August 2018 and August 2022, noting a higher incidence of associated malformations in omphalocele cases compared to gastroschisis.!
- Results indicated a higher mortality rate in gastroschisis cases (11 deaths) compared to omphalocele, with sepsis being the main cause of death, highlighting the need for improved management strategies in neonatal care.!
Outcomes of Gastroschisis and Omphalocele Treated at Children's Surgery Verified Centers in Texas.
J Surg Res
December 2024
Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas; Division of Pediatric Surgery, Department of Surgery, Texas Children's Hospital, Houston, Texas. Electronic address:
Introduction: Anterior abdominal wall defects (AWDs), such as gastroschisis or omphalocele, are often diagnosed prenatally and counseled to deliver at facilities with resources capable of managing their AWD and complex-associated anomalies. The American College of Surgeons instituted their Children's Surgery Verification (CSV) program to identify facilities with the optimal resources for pediatric surgical care. We aimed to evaluate the impact of CSV status on the outcomes of AWD and potential health disparities in the care of AWD in the first year of life in Texas.
View Article and Find Full Text PDFTemporal trends in the prevalence of major birth defects in China: a nationwide population-based study from 2007 to 2021.
World J Pediatr
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National Center for Birth Defects Monitoring, West China Second University Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Background: Birth defects constitute a significant public health issue worldwide, yet there is a lack of comprehensive population-based data for the Chinese population.
Methods: We analyzed data from the China National Population-based Birth Defects Surveillance System from 2007 to 2021, we calculated the prevalence rates of selected birth defects, stratified by maternal residence, geographic region, maternal age, and infant sex. The Joinpoint regression model was utilized to assess trends and annual percent changes in prevalence.
Optimal Strategies for Screening Common Birth Defects in Children of Low- and Middle-Income Countries: A Systematic Review.
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Institute for Global Health and Development, The Aga Khan University, Karachi, Pakistan.
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Article Synopsis
- Malrotation is a congenital condition that can lead to serious bowel issues, often diagnosed by age 1, but can sometimes be identified prenatally through imaging techniques.
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