Amiloride at millimolar concentrations caused marked changes in the growth-dependent intracellular balance of Na+ and K+ in Streptococcus faecalis. These results, whether specific to transport processes or resulting from indirect yet unknown mechanisms, constitute the first evidence of an effect of amiloride on bacterial electrolytes.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC284194PMC
http://dx.doi.org/10.1128/AAC.29.5.958DOI Listing

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