The review aims to examine the emergence and reemergence of infectious diseases in Jordan, in parallel with the Syrian refugee crisis. Qualitative approach has been adopted for systematically examining the outcomes of Syrian Crisis, which resulted with emerging and re-emerging infectious diseases. It has adhered that infectious diseases; including measles, tuberculosis, and Cutaneous Leishmaniasis, have hazardous effects on Syrian refugees along with alarming threats to local population in Jordan. National health policies should be implemented to adhere to the influence of infectious diseases beside the reduction of the extent of infectious diseases in Jordan. In the 21st century, Syrian conflict can be deliberated as one of the biggest humanitarian disasters. In this multifaceted emergency with devastating requirements and limitations, it has been found essential for dominant medical healthcare providers to develop medical strategies that are based on comprehensive understanding of concerned context and the main medical requirements and susceptible groups.

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