[This corrects the article DOI: 10.1007/s10433-018-0488-x.].
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http://dx.doi.org/10.1007/s10433-018-0489-9 | DOI Listing |
J Crohns Colitis
January 2025
Amsterdam UMC, Department of Gastroenterology and Hepatology, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Introduction: It remains unclear why up to 30% of ulcerative colitis patients (UC) do not respond to tumor necrosis factor inhibitors (TNFi). Validated biomarkers for (non-)response ((N)R) are lacking. Most studies investigating underlying mechanisms do not differentiate between pharmacokinetic and inflammatory mechanisms.
View Article and Find Full Text PDFSci Rep
November 2024
Group of Optics and Visual Perception, Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, 03016, Spain.
Immersive virtual reality (VR) is recently being explored as a therapeutic alternative for the treatment of amblyopia. This pilot study aimed to evaluate the preliminary efficacy, safety, usability and satisfaction obtained with the use of a novel VR system (NEIVATECH) to provide binocular vision training in previously treated older amblyopic children with non-compliance or non-response to patching. A prospective, multicentre, open-label, single-arm, pilot study was conducted in which the intervention under study was 9 h of therapy with the NEIVATECH system, distributed in 18 half-hour sessions spread over 1 month.
View Article and Find Full Text PDFFront Pediatr
July 2024
Department of Neonatology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, China.
Background: Circadian rhythms impact metabolism and the therapeutic effects of drugs. The purpose of this study was to determine the association between and polymorphisms and caffeine citrate treatment response in infants with apnea of prematurity.
Methods: A total of 221 preterm infants of gestational age <34 weeks were included in this study (160 in the response group and 61 in the non-response group).
Pediatr Res
July 2024
Department of Paediatric Gastroenterology Hepatology and Nutrition, University of Groningen, University Medical Center Groningen - Beatrix Children's Hospital, Groningen, the Netherlands.
Background: In a considerable proportion of anaemic children with inflammatory bowel disease (IBD), haemoglobin (Hb) does not normalise after iron therapy. We evaluated the added value of novel iron markers (hepcidin and soluble transferrin receptor [sTfR]) as compared to traditional iron markers (ferritin and transferrin saturation [TSAT]) to determine the best strategy for the prediction of non-responsiveness to iron suppletion.
Methods: In this secondary analysis of prospectively collected data, we measured iron markers in anaemic children (Hb Z-score < -2.
Gen Psychiatr
June 2024
Department of Neurosurgery, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, Shanghai, China.
Background: Structural imaging holds great potential for precise targeting and stimulation for deep brain stimulation (DBS). The anatomical information it provides may serve as potential biomarkers for predicting the efficacy of DBS in treatment-resistant depression (TRD).
Aims: The primary aim is to identify preoperative imaging biomarkers that correlate with the efficacy of DBS in patients with TRD.
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