A new phenanthropyran and a new biphenanthrene from the rhizomes of and their antioxidant activities.

Nat Prod Res

School of chemical engineering, Institute of pharmaceutical engineering technology and application, Analytical and testing center, Key laboratory of green chemistry of Sichuan institutes of higher education, Sichuan university of science & engineering, Zigong, People's Republic of China.

Published: August 2020

A new phenanthropyran, dioscorone B (), and a new phenanthrene (), together with seven known compounds (-), were isolated from the 75% ethanol extract of rhizomes. The chemical structures of these compounds were elucidated by comprehensive spectroscopic methods including NMR, HRESIMS, IR, and UV spectra. Compounds were first isolated from genus . The proton and carbon chemical shifts of compounds - were unambiguously assigned based on the 1D-NMR and 2D-NMR data. Compounds - and - were first tested for their antioxidant activities. Compounds and showed excellent activities with IC values of 0.07 ± 0.10 μM and 0.13 ± 0.09 μM, respectively.

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http://dx.doi.org/10.1080/14786419.2019.1585844DOI Listing

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