AI Article Synopsis
- No studies have previously examined the use of kidneys from pediatric donors with severe Hand, Foot, and Mouth Disease (HFMD).
- A retrospective analysis of six kidney transplant cases from four pediatric donors with severe HFMD was conducted, involving donors aged between 6 months and nearly 4 years and recipients aged 18 to 41.
- Follow-up results showed that all recipients, except one, maintained normal kidney function, with 100% recipient survival and 83.3% allograft survival, and none exhibited symptoms related to HFMD.
Article Abstract
No studies have reported making use of kidneys from pediatric donors with severe HFMD. Here, we retrospectively analyzed the feasibility and clinical effect of six cases of kidney transplantation from four pediatric donors with severe HFMD in our center between January 2014 and December 2016. The donors' age ranged from 6 months to 3 years and 11 months. The recipients' age ranged from 18 to 41 years. Single kidney transplantation was performed in four recipients, and dual splitting kidney transplantation and en bloc kidney transplantation were performed in two recipients, respectively. During the 1.5-4 years follow-up, all recipients maintained normal kidney allograft function except for one recipient whose allograft was removed due to the allograft artery thrombosis. The survival rates of recipient and allograft were 100% and 83.3%, respectively. None of the six recipients showed any symptoms associated with HFMD. In conclusion, it is feasible to perform kidney transplantation from pediatric donors with severe HFMD to adult recipients with immunity to the pathogens. The clinical effect is satisfactory.
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| http://dx.doi.org/10.1111/petr.13386 | DOI Listing |
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