Introduction: Septic arthritis by Aggregatibacter aphrophilus is an uncommon entity, so it's important to diagnose it early, to avoid serious consequences. In adults, the knee is the most affected site.
Methods: We present a case of a 17-year-old boy, with pain in the left knee since one month ago. It shows an increase in local temperature, erythema and movement inability. A nuclear magnetic resonance (NMR) was performed and empirical treatment was given with cephalothin and clindamycin. A knee arthrotomy was realized, and intramedullary secretion and bone tissue was sent to study.
Results: the NMR images were suggestive of an infectious process. In the culture gram-negative coccobacilli were isolated, later identified like as Aggregatibacter aphrophilus. According to this diagnostic, the treatment was changed to ceftriaxone
The Main Conclusions: the rapidity and certainty in the choice of antimicrobial therapy is the most important step for a well evolution of this infection, therefore is very important to emphasize the importance of a correct identification of these rare microorganisms
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http://dx.doi.org/10.31053/1853.0605.v76.n1.20011 | DOI Listing |
Int J Biol Macromol
December 2024
State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266237, China. Electronic address:
Hepatocellular carcinoma (HCC) significantly impacts human health due to its tendency to develop multi-drug resistance. Regarding the treatment of HCC, galactosylated conjugates can target drug delivery. Bacterial N-glycosyltransferases (NGTs) catalyze glucosylation or galactosylation of the Asn residue motif Asn-X-Ser/Thr (X ≠ P).
View Article and Find Full Text PDFSTAR Protoc
December 2024
Division of Oral Health and Periodontology, Department of Dental Medicine, Karolinska Institutet, Alfred Nobels Allé 8, 14104 Huddinge, Stockholm, Sweden. Electronic address:
J AAPOS
December 2024
McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Texas; Department of Ophthalmology and Visual Science, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Texas. Electronic address:
Infantile acute dacryocystitis is an acute inflammation of the lacrimal sac in infants. The most common pathogens are Gram-positive cocci and Gram-negative rods. We report a case of infantile polymicrobial acute dacryocystitis.
View Article and Find Full Text PDFIsr Med Assoc J
October 2024
Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel, Reichman University, Herzliya, Israel.
Respir Res
October 2024
Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium.
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