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| http://dx.doi.org/10.21037/hbsn.2018.11.08 | DOI Listing |
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Impact of parenchymal transection techniques on intraoperative blood loss during liver resection in a porcine model of elevated central venous pressure: A comparative study.
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Department of General, Visceral and Transplant Surgery, University Hospital Münster, Münster, Germany. Electronic address:
Introduction And Objectives: Liver resection is the standard treatment for resectable liver tumors and metastases. However, mortality and morbidity remain significant concerns, particularly for patients with chronically elevated central venous pressure (CVP), which increases perioperative complication risks. The optimal parenchymal transection technique for these patients remains unclear, necessitating further research.
View Article and Find Full Text PDFMRI Features and Neutrophil-to-Lymphocyte Ratio (NLR)-Based Nomogram to Predict Prognosis of Microvascular Invasion-Negative Hepatocellular Carcinoma.
J Hepatocell Carcinoma
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Department of Medical Imaging Center, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People's Republic of China.
Purpose: This study aimed to develop a novel nomogram to predict recurrence-free survival (RFS) for microvascular invasion (MVI)-negative hepatocellular carcinoma (HCC) patients after curative resection.
Patients And Methods: A total of 143 pathologically confirmed MVI-negative HCC patients were analyzed retrospectively. Baseline MRI features and inflammatory markers were collected.
Bridging Therapies-Ex Vivo Liver Xenoperfusion and the Role of Machine Perfusion: An Update.
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January 2025
Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Advancements in xenotransplantation intersecting with modern machine perfusion technology offer promising solutions to patients with liver failure providing a valuable bridge to transplantation and extending graft viability beyond current limitations. Patients facing acute or acute chronic liver failure, post-hepatectomy liver failure, or fulminant hepatic failure often require urgent liver transplants which are severely limited by organ shortage, emphasizing the importance of effective bridging approaches. Machine perfusion is now increasingly used to test and use genetically engineered porcine livers in translational studies, addressing the limitations and costs of non-human primate models.
View Article and Find Full Text PDFComplete transition from laparoscopic to robotic liver surgery achieves superior outcomes in difficult hepatectomies: a seven-year retrospective study.
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Department of Surgery, Weill Cornell Medicine, New York, NY, USA.
Background: Minimally invasive liver surgery (MILS) is superior to open surgery when considering decreased blood loss, fewer complications, shorter hospital stay, and similar or improved oncologic outcomes. However, operative limitations in laparoscopic hepatectomy have curved its applicability and momentum of complex minimally invasive liver surgery. Transitioning to robotic hepatectomy may bridge this complexity gap.
View Article and Find Full Text PDFPortal Vein Arterialization as a Lifesaving Strategy for Hepatic Artery Injury in Robotic Hepatectomy.
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Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Article Synopsis
- Robotic vascular resection and reconstruction is complex, and portal vein arterialization (PVA) is an effective alternative when the hepatic artery can't be repaired, enhancing liver oxygen supply and promoting regeneration.
- A case study describes a 52-year-old man with cholangiocarcinoma who underwent robotic left-liver-first surgery, but sustained an artery injury, leading to the use of PVA for successful artery-portal vein anastomosis.
- The surgery lasted 490 minutes with a blood loss of about 300 mL, and although there was a bile leak post-surgery, the patient recovered without experiencing liver failure.
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