AI Article Synopsis
- This study aimed to assess how socio-clinical factors influence adherence to antiretroviral treatment (ART) among people living with HIV/AIDS in Koula-Moutou, Gabon.
- Two methods were used to evaluate adherence: patient declarations and pharmacy visit compliance, revealing higher patient-reported adherence rates compared to actual pharmacy data.
- The study found a link between better reported adherence and lower education levels and calls for further research on ART adherence factors in this vulnerable population.
Article Abstract
The goal of this study was to evaluate the impact of socio-clinical factors on adherence to antiretroviral treatment in people living with HIV/AIDS in Koula-Moutou (a rural area of Gabon). Two adherence assessment methods based on patient declaration and compliance with pharmacy visits were used to determine qualitative and quantitative aspects of adherence to antiretroviral therapy (ART). The quantitative (82.2%) and qualitative (79.5%) adherences to ART declared by patients were higher than those obtained through pharmacy visit assessment methods (15.8% and 45.2%, respectively). Moreover, the declarative and pharmacy visit compliance methods showed fair agreement (quantitative Kappa = 0.317; qualitative Kappa = 0.311). A better quantitative or qualitative declarative adherence was associated with a lower level of education (P = 0.05 and P = 0.025 respectively). This study reported for the first time the factors influencing adherence to ART in a rural area of East Gabon. We recommend further investigations in a large cohort to better assess the impact of socio-clinical factors on ART adherence in a vulnerable group of patients.
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| http://dx.doi.org/10.2989/16085906.2018.1552878 | DOI Listing |
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