AI Article Synopsis
Article Abstract
Noninvasive ventilation (NIV) settings determined during wakefulness may produce patient-ventilator asynchrony (PVA) during sleep, causing sleep disruption and limiting tolerance. This study investigated whether NIV titrated with polysomnography (PSG) is associated with less PVA and sleep disruption than therapy titrated during daytime alone.Treatment-naive individuals referred for NIV were randomised to control (daytime titration followed by sham polysomnographic titration) or PSG (daytime titration followed by polysomnographic titration) groups. Primary outcomes were PVA and arousal indices on PSG at 10 weeks. Secondary outcomes included adherence, gas exchange, symptoms and health-related quality of life (HRQoL).In total, 60 participants were randomised. Most (88.3%) had a neuromuscular disorder and respiratory muscle weakness but minor derangements in daytime arterial blood gases. PVA events were less frequent in those undergoing polysomnographic titration (median (interquartile range (IQR)): PSG 25.7 (12-68) events·h control 41.0 (28-182) events·h; p=0.046), but arousals were not significantly different (median (IQR): PSG 11.4 (9-19) arousals·h control 14.6 (11-19) arousals·h; p=0.258). Overall adherence was not different except in those with poor early adherence (<4 h·day) who increased their use after polysomnographic titration (mean difference: PSG 95 (95% CI 29-161) min·day control -23 (95% CI -86-39) min·day; p=0.01). Arterial carbon dioxide tension, somnolence and sleep quality improved in both groups. There were no differences in nocturnal gas exchange or overall measures of HRQoL.NIV titrated with PSG is associated with less PVA but not less sleep disruption when compared with therapy titrated during daytime alone.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1183/13993003.02118-2018 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Polysomnographic and clinical characteristics of sleep apnea headache patients.
Sleep Breath
December 2024
Department of Neurology, University of Health Sciences Erenköy Mental Health and Neurological Diseases Training and Research Hospital, Istanbul, Turkey.
Article Synopsis
- Sleep apnea headache (SAH) is characterized as a recurring, throbbing headache that occurs upon waking, linked to obstructive sleep apnea syndrome (OSAS) and diagnosed through polysomnography with an apnea-hypopnea index of at least 5.
- A study performed at a sleep center analyzed clinical and polysomnographic data of patients with SAH, separating them into varying severities of OSAS, while excluding those with different morning headaches or under treatment.
- Results showed significant differences between patients with SAH and those without, including higher sleepiness scores and more frequent limb movement in SAH sufferers, alongside notable contrasts in sleep quality and wake times.
Role of Nasal Surgery in Adult Obstructive Sleep Apnea: A Systematic Review.
Sleep Sci
September 2024
Department of Otorhinolaryngology, Hospital Quirónsalud Marbella, Marbella, Málaga, Spain.
Article Synopsis
- This study reviews the effects of isolated nasal surgery on adults with obstructive sleep apnea (OSA) by analyzing data from multiple medical databases between December 2022 and March 2023.
- A total of 25 studies were included, indicating significant improvements in sleep quality, sleepiness, nasal resistance, and snoring after the surgery, although other objective sleep parameters did not change significantly.
- While not a primary treatment for OSA, isolated nasal surgery can enhance CPAP therapy effectiveness and compliance by reducing required pressures and improving subjective symptoms.
Sleep and follow-up characteristics of Hispanic patients: Insights from a comparative analysis with White patients in polysomnographic split-night studies.
Sleep Med
March 2024
University of California San Francisco, Fresno, CA, USA. Electronic address:
Background: Limited attention has been given to exploring the efficacy of titration in split-night polysomnography (PSG) and the factors influencing adherence to continuous positive airway pressure (CPAP) therapy. This study aims to evaluate the severity of OSA and PSG parameters in HP compared to WP.
Methods: Split-night PSG studies conducted on adults.
Purpose: To investigate the prevalence of treatment-emergent central sleep apnea (TECSA) in individuals with obstructive sleep apnea syndrome (OSAS) during continuous positive airway pressure (CPAP) titration and assess their polysomnographic characteristics.
Methods: A total of 116 patients with OSAS who underwent full-night CPAP titration at the Sleep Laboratory of Adana City Research and Education Hospital from September 2017 to January 2018 were recruited for the study. The patients' polysomnographic data related to respiratory events and sleep stages were reviewed in a retrospective manner.
Identifying Affecting Factors on Acceptance with CPAP on the First Night of PAP Titration in Sleep Clinic on Patients with Obstructive Sleep Apnea.
Iran J Otorhinolaryngol
November 2023
Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Introduction: This research examined the causes of low acceptance with Continuous Positive Airway Pressure Continuous Positive Airway Pressure (CPAP) especially anatomical causes and if eliminating them would result in increasing its adherence.
Materials And Methods: This cross sectional study was performed on patients with moderate to severe Obstructive Sleep Apnea Obstructive Sleep Apnea (OSA) undergoing PAP titration in the sleep clinic. CPAP acceptance was evaluated by visual analog scale (VAS) about mask and sleep satisfaction and the possibility of using CPAP in the future, mask complications, physical examination of the upper airway and polysomnographic (PSG) results before and after titration.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!