Sustained Remission of Eosinophilic Esophagitis Following Discontinuation of Dietary Elimination in Children.

Clin Gastroenterol Hepatol

Institute of Gastroenterology, Nutrition, and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Published: January 2020

AI Article Synopsis

  • Eosinophilic esophagitis (EoE) can worsen from inflammation to a more severe form if not properly treated, leading to long-term management recommendations.
  • A group of children with EoE successfully achieved both clinical and histologic remission by following elimination diets.
  • Remarkably, these children maintained sustained untreated remission even after reintroducing all previously eliminated food allergens.

Article Abstract

Eosinophilic esophagitis (EoE), when left untreated, may progress from an inflammatory to a fibrostenotic phenotype. Inflammation generally recurs after treatment withdrawal. Thus, long-term treatment has been recommended. Here, we describe a cohort of children with EoE who achieved clinical and histologic remission with elimination diets, and maintained sustained untreated remission (SUR) despite re-introduction of all eliminated food allergens.

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http://dx.doi.org/10.1016/j.cgh.2019.03.008DOI Listing

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