The impact of chlorhexidine gluconate on the skin microbiota of children and adults: A pilot study.

Am J Infect Control

Division of Infectious Disease, University of Wisconsin School of Medicine & Public Health, Madison, WI; Department of Medicine, William S. Middleton Memorial Veterans Hospital, Madison, WI.

Published: August 2019

We examined the effect of chlorhexidine gluconate (CHG) bathing on the skin microbiota of adult and pediatric patients. We observed no differences in pediatric patients; however, multiple genera of bacteria were observed to be significantly less abundant in the adults bathing with CHG. Further research is needed to determine the long-term impact of CHG use on the skin microbiota.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736594PMC
http://dx.doi.org/10.1016/j.ajic.2019.01.024DOI Listing

Publication Analysis

Top Keywords

skin microbiota
12
chlorhexidine gluconate
8
pediatric patients
8
impact chlorhexidine
4
gluconate skin
4
microbiota children
4
children adults
4
adults pilot
4
pilot study
4
study examined
4

Similar Publications

An Infrequent Guest in Orthopedic Infections.

Surg Infect (Larchmt)

January 2025

CIBERINFEC, CIBER de Enfermedades Infecciosas, Madrid, Spain.

is a species of anaerobic gram-positive coccus considered part of human microbiota. It has been described as a cause of skin and soft tissue infections, but it is not a common cause of operation-related infections. Describe the characteristics, treatment, and results of musculoskeletal infection by treated in our center.

View Article and Find Full Text PDF

Background: Data from observational and clinical studies indicate an association between skin microbiota and hidradenitis suppurativa (HS). However, the causal relationship between skin microbiota and HS remains to be elucidated.

Methods: We obtained data on skin microbiota and HS from summary statistics of genome-wide association studies and applied Mendelian randomization (MR) statistical methods to assess causality.

View Article and Find Full Text PDF

Reactive B-cell rich lymphoid proliferation (rB-LP), once called pseudolymphoma, is a benign lymphoproliferative disorder, which is histologically characterized by dense dermal infiltrate forming reactive germinal centers with tingible body macrophages. The disease frequently involves the face, scalp, and ear lobes. Treatment includes topical or intralesional steroids, surgical resection, ultraviolet therapy, laser treatment, and radiation therapy.

View Article and Find Full Text PDF

Pharyngeal Microbiome in Atopic Dermatitis: A 16S rRNA Sequencing Study.

Exp Dermatol

January 2025

Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.

While recent studies have demonstrated the involvement of the skin and gut microbiome in the pathogenesis of atopic dermatitis (AD), the influence of pharyngeal microbiota on AD remains unclear. This study aims to explore disparities in the composition of pharyngeal flora among AD patients and their potential role in the pathogenesis of AD. Between March and May 2023, 30 patients with AD at the outpatient department of Jiangsu Provincial Traditional Chinese Medicine Hospital were recruited, along with 20 healthy subjects, underwent 16S rRNA sequencing on pharyngeal swabs.

View Article and Find Full Text PDF

The human skin and oral cavity harbor complex microbial communities, which exist in dynamic equilibrium with the host's physiological state and the external environment. This study investigates the microbial atlas of human skin and oral cavities using samples collected over a 10-month period, aiming to assess how both internal and external factors influence the human microbiome. We examined bacterial community diversity and stability across various body sites, including palm and nasal skin, saliva, and oral epithelial cells, during environmental changes and a COVID-19 pandemic.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!