Purulent Pericarditis in Sickle Cell Disease Due to ; a Unique Case Report and Literature Review.

Hemoglobin

a Downstate College of Medicine, Department of Medicine, Division of Hematology-Oncology , State University of New York, Brooklyn , NY , USA.

Published: January 2019

Purulent pericarditis is a localized infection with a thick, fibrinous hypercellular exudate and is historically associated with a high mortality. We describe a case of purulent pericarditis due to in a 30-year-old woman with sickle cell disease who presented with fever, dyspnea, and septicemia. Despite timely initiation of antibiotics, she developed a large purulent pericardial effusion requiring surgical pericardiocentesis followed by a pericardial window. At 14 months follow-up, she has remained asymptomatic without sequelae. A review of the literature contained only four patients with purulent pericarditis in sickle cell patients. We discuss the unique aspects of this case in the context of purulent pericarditis in the age of modern antibiotics and hypothesize on the pathogenesis of delayed pericardial effusion after pericarditis.

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http://dx.doi.org/10.1080/03630269.2019.1579736DOI Listing

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