Using limited proteolysis and scanning microcalorimetry it was shown that each terminal part of the fibrinogen molecule is constituted by four co-operative domains. Among these domains two strongly interacting domains are formed by the C-terminal part of the beta-chain, while the two other domains are formed by the C-terminal part of the gamma-chain.
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| http://dx.doi.org/10.1016/0014-5793(86)80705-0 | DOI Listing |
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