Photoacoustic ultrasound excitation has great potential in structural nondestructive testing and applications for medical treatments as a promising alternative to electrical ultrasound. This study proposes and demonstrates a multipoint optical fiber laser-ultrasonic transducer system, wherein the fiber-optic ultrasonic transducer is fabricated by a coreless fiber segment's fusion with single-mode fibers at each end. Simulation and experiment results show that the transducer coupling ratio is dependent on the coreless fiber's length. The structure of such an ultrasonic transducer is easily manufactured. Thus, the structures of these optical fiber ultrasonic transducers with different coupling ratios are connected in the order of small to large coupling ratios. In this manner, multipoint ultrasonic excitation with equal intensities at each excitation point can be obtained using this simple and low-cost method. Using laser guidance through the optical fiber to generate ultrasound can efficiently solve some shortcomings of traditional ultrasonic transducers, such as large volume, small bandwidth, and electromagnetic interference. Moreover, this type of fiber-optic ultrasound transducer has higher mechanical strength than other fiber-optic ultrasound transducers and is expected to be useful in structural health-monitoring of buildings.
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http://dx.doi.org/10.1364/OE.27.006116 | DOI Listing |
RSC Adv
January 2025
College of Electronic Engineering, Huainan Normal University Huainan 232038 China
An erbium-doped fiber ring laser based on a single-mode fiber-no-core fiber-single-mode fiber (SMF-NCF-SMF) structure was constructed and experimentally demonstrated for label-free DNA hybridization measurement. The SMF-NCF-SMF structure acts as a sensing element and a filter to select the laser wavelength. The proposed fiber ring laser sensor exhibits a high optical signal-to-noise ratio (SNR, >50 dB) and narrow full width at half maximum (FWHM, <0.
View Article and Find Full Text PDFBMC Ophthalmol
January 2025
Department of Refractive Surgery, Guangzhou Aier Eye Hospital, Jinan University, Guangzhou City, Guangdong Province, 510000, China.
Purpose: To evaluate the impact of Implantable Collamer Lens (ICL) implantation on anterior chamber angle parameters and posterior segment structures in highly myopic eyes and explore potential correlations between these changes. The study aimed to assess alterations in superficial and deep vessel density (SVD, DVD), foveal avascular zone (FAZ) area, and retinal nerve fiber layer (RNFL) thickness to clarify the safety profile of ICL implantation.
Methods: Prospective observational study, included 36 highly myopic eyes undergoing ICL implantation in surgery group and 23 non-surgical control eyes in non-surgery group.
Cardiovasc Res
January 2025
Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Aims: Dedicator of Cytokinesis 2 (DOCK2), a member of the DOCK family of Guanine nucleotide exchange factors that specifically act on the Rho GTPases including Rac and Cdc42, plays pivotal roles in the regulation of leukocyte homeostasis. However, its functions in platelets remain unknown.
Methods And Results: Using mice with genetic deficiency of DOCK2 (Dock2-/-), we showed that Dock2-/-mice exhibited a macrothrombocytopenic phenotype characterized as decreased platelet count and enlarged platelet size by transmission electron microscopy.
Cell Biochem Biophys
January 2025
Department of Electronics and Communication Engineering, Hajee Mohammad Danesh Science and Technology University, Dinajpur, 5200, Bangladesh.
Blood components play a crucial role in maintaining human health and accurately detecting them is essential for medical diagnostics. A cutting-edge sensor utilizing PCF revealed to precisely identify a wide range of blood components with WBCs (white blood cells), RBCs (red blood cells), HB (hemoglobin), platelets, and plasma. A numerical analysis was performed using COMSOL Multiphysics software to assess the capabilities of the sensor.
View Article and Find Full Text PDFJ Mater Chem B
January 2025
Department of Optical and Biophysical Systems, Institute of Physics of the Czech Academy of Sciences, Prague, 18200, Czech Republic.
DNA nanostructures (DNs) have gained popularity in various biomedical applications due to their unique properties, including structural programmability, ease of synthesis and functionalization, and low cytotoxicity. Effective utilization of DNs in biomedical applications requires a fundamental understanding of their interactions with living cells and the mechanics of cellular uptake. Current knowledge primarily focuses on how the physicochemical properties of DNs, such as mass, shape, size, and surface functionalization, affect uptake efficacy.
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