For a significant number of people with visual impairments, public transport plays an important role in productivity, community participation, and independence, since it may be the only feasible mobility option to participate in their education, work, medical care, food, and to attend many other places in their community. To use the public bus system safely, effectively, and autonomously, these people need to collect information about their physical environment and visible information at stops and terminals, such as timetables, routes, etc. Unfortunately, most people who are blind or visually impaired experience difficulties in getting on the right bus or getting off at the right destination. These situations usually force them to depend on other people that assist them in activities close to their homes, or settle for simpler jobs, or simply stay at home. Therefore, our efforts should aim to develop a system where technology is used to empower people with visual disabilities, allowing them to navigate autonomously in the public transport system. This paper presents a system based on radio frequency (RF) communication proposed within the framework of the MOVIDIS (Mobility for Visually Disabled People) research project (funded by the National Secretariat of Science, Technology and Innovation-SENACYT, under Grants No. 109-2015-4-FID14-073 and No. 99-2018-4-FID17-031), which provides an alternative to assist people with visual disabilities with their mobility in the public transport system. The various modules of this system communicate with each other by means of radio frequency and allow users to interact with buses and their respective stops. The first experimental results show that RF communication represents a viable option to help people with visual disabilities in public transport services.
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http://dx.doi.org/10.3390/s19061282 | DOI Listing |
Front Public Health
January 2025
Department of Surgery, University of California, San Francisco, San Francisco, CA, United States.
Background: Shared micromobility programs (SMPs) are integral to urban transport in US cities, providing sustainable transit options. Increased use has raised safety concerns, notably about helmet usage among e-scooter and e-bicycle riders. Prior studies have shown that head and upper extremity injuries have risen with SMP adoption, yet data on helmet use remains sparse.
View Article and Find Full Text PDFAlzheimers Dement
January 2025
Department of Neurological Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Introduction: Whole genome methylation sequencing (WGMS) in blood identifies differential DNA methylation in persons with late-onset dementia due to Alzheimer's disease (AD) but has not been tested in persons with mild cognitive impairment (MCI).
Methods: We used WGMS to compare DNA methylation levels at 25,244,219 CpG loci in 382 blood samples from 99 persons with MCI, 109 with AD, and 174 who are cognitively unimpaired (CU).
Results: WGMS identified 9756 differentially methylated positions (DMPs) in persons with MCI, including 1743 differentially methylated genes encoding proteins in biological pathways related to synapse organization, dendrite development, and ion transport.
J Nutr
December 2024
Division of Reproductive Sciences, Department of Obstetrics & Gynecology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Section of Neonatology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address:
Pregnancies complicated by maternal obesity are characterized by metabolic differences affecting placental nutrient transport and fetal development. Docosahexaenoic acid (DHA) is critical for fetal brain development and is primarily incorporated into phosphatidylcholine (PC). Recent evidence suggests choline may enhance PC-DHA synthesis; however, data on the impact of maternal plasma choline on placental phospholipid DHA content in females with obesity are limited.
View Article and Find Full Text PDFEur J Pharm Sci
December 2024
Center of Drug Absorption and Transport, Department of Biopharmaceutics and Pharmaceutical Technology, Institute of Pharmacy, University of Greifswald, Felix-Hausdorff-Str. 3, 17489 Greifswald, Germany.
Older people represent approximately 20% of the Polish population and are the primary population using medications. Behaviours connected with drug intake (such as dosage form modifications, type and amount of fluid and/or food accompanying administration) are crucial for drug efficacy and avoidance of adverse effects. The presented study had three research aims; firstly, to investigate the real-life drug administration process among older adults and geriatric patients in Poland.
View Article and Find Full Text PDFAm J Psychiatry
January 2025
Directorate of Behavioral Health, Walter Reed National Military Medical Center, Bethesda, MD (Wolfgang); Departments of Psychiatry (Wolfgang) and Medical and Clinical Psychology (Gray), Uniformed Services University, Bethesda, MD; Departments of Psychiatry (Wolfgang, Krystal), Neuroscience (Krystal), and Psychology (Krystal), Yale University School of Medicine, New Haven, CT; Center for Psychedelic Research and Therapy, Department of Psychiatry and Behavioral Sciences, The University of Texas at Austin Dell Medical School (Fonzo, Nemeroff); Department of Psychiatry & Biobehavioral Sciences, David Geffen School of Medicine, UCLA (Grzenda); Department of Psychiatry & Behavioral Sciences, University of Minnesota, Minneapolis (Widge); Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham (Kraguljac); Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald); Department of Psychiatry and Behavioral Sciences, Stanford University and Veterans Affairs Palo Alto Health Care System, Palo Alto, CA (Rodriguez).
MDMA (i.e., 3,4-methylenedixoymethamphetamine), commonly known as "Ecstasy" or "Molly," has been used since the 1970s both in recreational and therapeutic settings.
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