Very weak left/right asymmetry in reflection and transmission is offered by a layer of a topological insulator on top of a layer of an anisotropic dielectric material, but it can be enhanced very significantly by using a periodic multilayer of both types of materials. This is an attractive prospect for realizing one-way terahertz devices, because both types of materials can be grown using standard physical-vapor-deposition techniques.
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Comparative transcriptomic analysis of left-right sensory differences in Haliotis discus hannai.
Comp Biochem Physiol Part D Genomics Proteomics
January 2025
School of Fisheries, Ludong University, Yantai 264025, China. Electronic address:
Asymmetric development, in which functional differences occur between left-right symmetrical organs, is widespread in organisms, including fish and mollusks. However, the asymmetry of symmetrical sensory structures in Haliotis discus hannai, a gastropod with a sensitive sensory system, remains unknown. This study analyzed the transcriptomes of three sensory structures (eyestalks, cephalic tentacles, and epipodial tentacles) to explore potential asymmetries in this species.
View Article and Find Full Text PDFFunction of nodal cilia in left-right determination: Mechanical regulation in initiation of symmetry breaking.
Biophys Physicobiol
September 2024
Department of Cell Biology, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Visceral organs in vertebrates are arranged with left-right asymmetry; for example, the heart is located on the left side of the body. Cilia at the node of mouse early embryos play an essential role in determining this left-right asymmetry. Using information from the anteroposterior axis, motile cilia at the central region of the node generate leftward nodal flow.
View Article and Find Full Text PDFLeft-Right Brain-Wide Asymmetry of Neuroanatomy in the Mouse Brain.
Neuroimage
January 2025
Department of Genetics, Harvard Medical School, Boston, MA, USA; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA. Electronic address:
Left-right asymmetry of the human brain is widespread through its anatomy and function. However, limited microscopic understanding of it exists, particularly for anatomical asymmetry where there are few well-established animal models. In humans, most brain regions show subtle, population-average regional asymmetries in thickness or surface area, alongside a macro-scale twisting called the cerebral petalia in which the right hemisphere protrudes anteriorly past the left.
View Article and Find Full Text PDFSonic Hedgehog signaling regulates the optimal differentiation pace from early-stage mesoderm to cardiogenic mesoderm in mice.
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Division of Anatomy and Developmental Biology, Department of Anatomy, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Sonic Hedgehog (Shh), encoding an extracellular signaling molecule, is vital for heart development. Shh null mutants show congenital heart disease due to left-right asymmetry defects stemming from functional anomaly in the midline structure in mice. Shh signaling is also known to affect cardiomyocyte differentiation, endocardium development, and heart morphogenesis, particularly in second heart field (SHF) cardiac progenitor cells that contribute to the right ventricle, outflow tract, and parts of the atrium.
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Clin Orthop Relat Res
January 2025
School of Biomedical Sciences, The University of Queensland, St. Lucia, Australia.
Background: Adolescent idiopathic scoliosis (AIS) is characterized by an asymmetrical formation of the spine and ribcage. Recent work provides evidence of asymmetrical (right versus left side) paraspinal muscle size, composition, and activation amplitude in adolescents with AIS. Each of these factors influences muscle force generation.
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