The authors report on their experience with high energy radiation therapy in early-stage (I/II) carcinomas of the prostate. Among 191 cases of biopsy-proved carcinomas of the prostate, there were 111 stage I and II tumors, including 83 T1, T2 intracapsular tumors. 78 of the 111 patients received curative radiation therapy. Delivered doses did not exceed 65 to 70 grays to the prostate and 50 grays to the pelvis. High energy radiation was used. Extension of the lesions was determined using lymphography, abdominal and pelvic CT, and surgical removal of lymph nodes. Among the 78 irradiated patients, success rates at five years were 65% for the 52 T1-T2 tumors and 38% for the 26 T3 N0 tumors. Selection of patients, technical conditions and long term results are discussed, as well as the problems met in determining the stage of the tumor accurately. High energy radiation therapy can control localized carcinomas with a satisfactory quality of survival.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Hydrogeochemical characterization of shallow and deep groundwater for drinking and irrigation water quality index of Kathmandu Valley, Nepal.
Environ Geochem Health
January 2025
Environment Research Laboratory, Faculty of Science, Nepal Academy of Science and Technology, Khumaltar, Lalitpur, Nepal.
A comprehensive hydrogeochemical analysis of 156 groundwater samples (106 shallow and 50 deep) was conducted in the Kathmandu Valley, Nepal. This study addresses a significant research gap by focusing on the hydro-geochemical composition and contamination of groundwater in the Kathmandu Valley, an area with limited detailed assessments. The novelty of this work lies in its comprehensive analysis of both shallow and deep groundwater, particularly concerning the high concentration of contaminants like arsenic, microbial pathogens, and ammonium, which are critical for public health.
View Article and Find Full Text PDFPharmacoinformatics-based screening and construction of a neutralizing anti-SARS-CoV-2 camelidae nanobody drug conjugate.
Mol Divers
January 2025
Department of Biochemistry, University of Delhi South Campus, Benito Juarez Road, Dhaula Kuan, New Delhi, 110021, India.
Nanobodies or variable antigen-binding domains (VH) derived from heavy chain-only antibodies (HcAb) occurring in the Camelidae family offer certain superior physicochemical characteristics like enhanced stability, solubility, and low immunogenicity compared to conventional antibodies. Their efficient antigen-binding capabilities make them a preferred choice for next-generation small biologics. In the present work, we design an anti-SARS-CoV-2 bi-paratopic nanobody drug conjugate by screening a nanobody database.
View Article and Find Full Text PDFSeasonal trends and sources of dicarboxylic acids in fine aerosol over the Brahmaputra valley, North-East India.
Environ Sci Pollut Res Int
January 2025
Department of Civil Engineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, 208016, India.
The atmospheric dicarboxylic acids (DCAs) have a significant impact on the climate and indirectly affect human health, making them important organic substances. PM bound DCAs were analysed for Jorhat, India, 2019. In addition to the temporal variability, seasonal variation throughout the year and the impact of varying meteorological factors on DCAs concentration have also been studied.
View Article and Find Full Text PDFPhysicochemical and Microbiological Quality Assessment of Artisanal and Commercial Recipes of Cucurbita ficifolia Jams with High Sensory Acceptability.
Plant Foods Hum Nutr
January 2025
PRONOA Laboratory, CIITeD- CONICET Jujuy National University, Italo Palanca 10, San, Salvador de Jujuy, 4600, Argentina.
Artisanal cayote jam consumption is widespread in Latin-American countries. This jam is prepared from the pulp of Cucurbita ficifolia Bouché. Here, an artisanal cayote jam recipe and a reduced-calorie artisanal cayote jam recipe were defined through sensory analysis.
View Article and Find Full Text PDFConfined active area and aggregation kinetic-based AuNPs@PVP nanosensors for simultaneous colorimetric detection of cysteine and homocysteine as homologues in human urine and serum.
Mikrochim Acta
January 2025
College of Chemistry, Chemical Engineering & Environmental Science, Minnan Normal University, Zhangzhou, 363000, China.
The detection of cysteine (Cys) and homocysteine (Hcy) in biological fluids has great significance for early diagnosis, including Alzheimer's and Parkinson's disease. The simultaneous determination of Cys and Hcy with a single probe is still a huge challenge. To enlarge the differences in space structure (line and ring) and energy (-721.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!