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Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
University of California, Irvine, Irvine, CA, USA.
Background: Family caregivers of persons with dementia (PWD) suffer from constant caregiving burden resulting in poor sleep quality. Understanding sleep parameters (e.g.
View Article and Find Full Text PDFPharmacokinetics and Bioequivalence of Two Fixed-Dose Combination Tablets of Valsartan/Amlodipine (80/5 Mg) in Healthy Chinese Subjects.
Drug Des Devel Ther
January 2025
Clinical Trial Center, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, 313000, People's Republic of China.
Purpose: The study aimed to investigate the pharmacokinetics and bioequivalence of coformulations of valsartan and amlodipine in healthy Chinese subjects under both fasting and fed conditions.
Methods: The research was conducted under both fasting and fed studies and employed a single-center, randomized, open-label, single-dose, three-period design with partial-repeat and crossover elements. A total of 71 healthy Chinese adult participants were included under fasting (n = 36) and fed (n = 35) conditions.
Robot-Assisted Gait Training for Achieving Gait Symmetry in a Subacute Stroke Patient: A Case Report.
Cureus
December 2024
Department of Rehabilitation, Musashigaoka Hospital, Kumamoto, JPN.
Gait asymmetry in post-stroke patients is an important gait characteristic that is associated with their balance control, inefficiency, and risks of musculoskeletal injury to the non-paretic lower limb and falling. Unfortunately, most stroke patients retain an asymmetrical gait pattern, even though their gait independence and gait speed improve. We describe the clinical course of a subacute stroke patient who achieved a symmetrical gait at discharge after undergoing both gait training with orthoses and robot-assisted gait training from the early intervention phase.
View Article and Find Full Text PDFUltrafast MRI for Pediatric Brain Assessment in Routine Clinical Practice.
Korean J Radiol
January 2025
Department of Radiology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Objective: To assess the feasibility of ultrafast brain magnetic resonance imaging (MRI) in pediatric patients.
Materials And Methods: We retrospectively reviewed 194 pediatric patients aged 0 to 19 years (median 10.2 years) who underwent both ultrafast and conventional brain MRI between May 2019 and August 2020.
Prospective Evaluation of Accelerated Brain MRI Using Deep Learning-Based Reconstruction: Simultaneous Application to 2D Spin-Echo and 3D Gradient-Echo Sequences.
Korean J Radiol
January 2025
Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.
Objective: To prospectively evaluate the effect of accelerated deep learning-based reconstruction (Accel-DL) on improving brain magnetic resonance imaging (MRI) quality and reducing scan time compared to that in conventional MRI.
Materials And Methods: This study included 150 participants (51 male; mean age 57.3 ± 16.
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