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Are Seed Oils the Culprit in Cardiometabolic and Chronic Diseases? A Narrative Review.
Nutr Rev
January 2025
Faculty of Medicine, Pelita Harapan University, Tangerang, Banten 15811, Indonesia.
The demonization of seed oils "campaign" has become stronger over the decades. Despite the dietary guidelines provided by nutritional experts recommending the limiting of saturated fat intake and its replacement with unsaturated fat-rich food sources, some health experts ignore the dietary guidelines and the available human research evidence, suggesting the opposite. As contrarians, these individuals could easily shift public opinion so that dietary behavior moves away from intake of unsaturated fat-rich food sources (including seed oils) toward saturated fats, which is very concerning.
View Article and Find Full Text PDFStigma in substance-based and behavioural addictions: A systematic review.
J Behav Addict
January 2025
1College of Education, Psychology & Social Work, Flinders University, Australia.
Background And Aims: The study of stigma contributes greatly to our understanding of individuals' experiences of mental disorders. Addictive disorders are often associated with public misconceptions of the disorder, which can contribute to shame, discrimination, and reticence to seek help. This review aimed to: (1) evaluate the nature, frequency, and prevalence of addiction stigma; (2) identify the correlates of addiction stigma; and (3) examine the psychometric qualities of addiction stigma measures.
View Article and Find Full Text PDFCurrent trends in antimicrobial use and the role of antimicrobial stewardship in palliative oncology: a narrative review.
BMC Palliat Care
January 2025
Division of Infectious Diseases, Department of Internal Medicine, and Center for Infectious Diseases Research, American University of Beirut Medical Center, PO Box 11-0236, Riad , Beirut, 1107 2020, Lebanon.
Background: The overuse of antimicrobials is prevalent in palliative oncology care, with up to 86.9% of terminal cancer patients receiving these agents during end-of-life care. This overutilization stems from recurrent infections due to immunosuppression, malnutrition, and frequent hospitalizations, as well as difficulty differentiating infection-related symptoms from cancer-related complications.
View Article and Find Full Text PDFThe prebiotic landscape: history, health and physiological benefits, and regulatory challenges - an IPA perspective part 1.
Benef Microbes
January 2025
Beneficial MicrobesConsultancy, Johan Karschstraat 3, 6709 TN Wageningen, The Netherlands.
Prebiotics are becoming increasingly recognized by consumers, health care professionals and regulators as important contributors to health. Nonetheless, the development, progress, and adoption of prebiotics is hindered by loose terminology, various misconceptions about sources and types of compounds that may be classified as prebiotics, and the lack of consensus on a definition that satisfies regulators. Evolving knowledge of the microbiome and its effects on host health has generated opportunities for modulation of the microbiota that can support host health.
View Article and Find Full Text PDFEvaluating student understanding of core pharmacokinetic concepts.
Eur J Pharmacol
January 2025
Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Australia. Electronic address:
Both educators and graduates have expressed concern about a perceived pharmacology knowledge gap that includes difficulty applying fundamental principles to clinical and research problems. Consequently, we sought to determine the extent to which current students can explain the meaning of, and appropriately apply, a subset of core concepts, and to identify any misconceptions arising from the responses. Of the twenty-four pharmacology core concepts arising from the recent international collaboration, four pharmacokinetic concepts were chosen, namely drug bioavailability, drug clearance, volume of distribution, and steady-state concentration.
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