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A combined treatment regimen for infection in in southern China.
Int J Parasitol Parasites Wildl
April 2025
State Key Laboratory for Animal Disease Control and Prevention, Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong, 510642, China.
The Sichuan snub-nosed monkey () is an endangered species in China and is susceptible to infection with species. However, the worms are difficult to remove completely. A practical treatment regimen for trichuriasis was conducted over a seven-month period on 15 in a wildlife zoo in southern China.
View Article and Find Full Text PDFKnowledge, attitudes and practices of Australian dairy goat farmers towards the control of gastrointestinal parasites.
Parasit Vectors
January 2025
Melbourne Veterinary School, The University of Melbourne, Werribee, VIC, 3030, Australia.
Background: Gastrointestinal parasites such as nematodes and coccidia are responsible for significant economic losses in the goat industry globally. An indiscriminate use of antiparasitic drugs, primarily registered for use in sheep and cattle, in goats has resulted in drug-resistant gastrointestinal parasites. Very little is known about the gastrointestinal parasite control practices used by Australian dairy goat farmers that are pivotal for achieving sustainable control of economically important parasites.
View Article and Find Full Text PDFDrug combination assays using Caenorhabditis elegans as a model system.
J Pharmacol Toxicol Methods
January 2025
Instituto de Investigaciones Bioquímicas de Bahía Blanca, Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur (UNS)-CONICET, 8000 Bahía Blanca, Argentina.
The C. elegans drug combination assay evaluates the effects of drug combinations in the nematode Caenorhabditis elegans, serving as a valuable tool to assess the efficacy of pharmaceutical agents and natural compounds. Using C.
View Article and Find Full Text PDFBiosynthesis of Zinc Oxide Nanoparticles by Origanum majorana Aqueous Leaves Extracts, Characterization and Evaluated Against to Schistosoma haematobium.
J Biomed Mater Res B Appl Biomater
February 2025
Zoology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.
Schistosomiasis, caused by Schistosoma worms, is a major neglected tropical disease in Africa, this disease is ranked as second after malaria. Nanotechnology is important for treating schistosomiasis while minimizing chemotherapy side effects. The current investigate aimed to assess the effectiveness of biosynthesized zinc oxide nanoparticles (ZnO NPs), which were used for the first time in an attempt to find alternative treatment for schistosomiasis and synthesized by Origanum majorana, and to compare them with praziquantel (PZQ), the only chemical treatment approved by the World Health Organization.
View Article and Find Full Text PDFColchicine: A Dual Therapeutic Target for Trichinellosis.
Acta Parasitol
January 2025
Department of Medical Parasitology, Faculty of Medicine, Zagazig University, El Kawmia Square, Zagazig, Sharkia Governorate, Egypt.
Purpose: Trichinellosis affects around 11 million people globally. Treatments for this medical condition are limited by adverse effects and resistance, emphasising the importance of effective and safe therapies. Consequentially, we sought to study colchicine's synergistic effects with atorvastatin or acetazolamide in the treatment of Trichinella spiralis (T.
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