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[Open transgastric necrosectomy for extended walled-off pancreas necrosis]. | LitMetric

AI Article Synopsis

  • The study focuses on the optimal timing for necrosectomy in severe acute pancreatitis, recommending a delay of 4-6 weeks after the disease onset to allow for walled-off pancreatic necrosis (WOPN) to develop.
  • The authors conducted 17 open transgastric necrosectomies on patients with extended WOPN, emphasizing that prior treatments were used for several months, and no surgical complications were reported post-operation.
  • Results showed a low mortality rate of 5.9%, and the procedure was effective in preventing further pancreatic complications, making it a safe option for treating extended WOPN.

Article Abstract

Aims: In severe acute pancreatitis the timing of necrosectomy is ideally should be postponed 4-6 weeks after the onset of the disease when the walled-of pancreatic necrosis (WOPN) has developed. The authors present their experience with open transgastric necrosectomy for extended WOPN.

Patients And Methods: The authors performed 17 (12 male, 5 female with a mean age of 61.6 ± 15.1 years) open transgastric necrosectomies for extended WOPN in a period of 1, January 2012 and 31, December 2017. Before the operations conservative and semiconservative therapy was used for an average of 74.6 ± 83.1 days. The mean size of the WOPNs was 13.8 ± 5.2 cm with localisation of the retrocolic and retroduodenal regions. All necroses were septic.

Results: Complications related to the operation were not observed. The mean time of hospitalization after the surgery was 11.6 ± 12.8 days. The mortality rate was 5.9%. Late operation or other interventions for pseudocyst or pancreas fistula formation was not performed. Two patients needed endoscopic dilatation with lavage in the early postoperative period because of fever. New diabetes mellitus was not observed but worsening of previously existed diabetes developed in 6.3% of the cases.

Conclusions: The open transgastric necrosectomy is safe and effective for extended WOPN. The advantage of this type of necrosectomy is the prevention of pancreatic pseudocyst and fistula formation.

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Source
http://dx.doi.org/10.1556/1046.72.2019.1.2DOI Listing

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