Long-acting reversible contraception. Long-acting reversible contraception (LARC) have a long-prolonged efficacy over 3 to 5 years depending on the method. They have become in recent years a subject of major interest in contraception. Indeed, these contraceptive methods, including intrauterine devices and the subcutaneous implant, allow obtaining an optimal contraceptive effectiveness while reducing the constraints for the women. All these contraceptions require the participation of an experienced professional for their placement and withdrawal. These LARCs may usually be suitable for all women after removal of rare contraindications. For each LARC, the potential advantages and disadvantages must be taken into account in order to choose the most appropriate method for each woman. Regular monitoring is always required to allow premature withdrawal in case of side effects, incident or wish to pregnancy. Their reversibility is immediate.
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BMJ Sex Reprod Health
January 2025
Obstetrics and Gynaecology, University of Edinburgh, Edinburgh, UK.
Background: Recent media attention has been given to an apparent shift away from hormonal methods of contraception. While an increase in fertility awareness-based or 'natural' family planning methods is reported in the grey literature, there are no robust data to determine any such trend in the UK.
Methods: We compared self-reported contraceptive use at conception among patients presenting for abortion at British Pregnancy Advisory Service from January to June 2018 (N=33 495) and January to June 2023 (N=55 055) using chi-square (χ) tests of association.
J Natl Cancer Inst
January 2025
School of Public Health, University of Queensland, Brisbane, QLD 4006, Australia.
Background: Use of long-acting, reversible contraceptives has increased over the past 20 years, but an understanding of how they could influence cancer risk is limited.
Methods: We conducted a nested case-control study among a national cohort of Australian women (n = 176 601 diagnosed with cancer between 2004 and 2013; 882 999 matched control individuals) to investigate the associations between the levonorgestrel intrauterine system, etonogestrel implants, depot-medroxyprogesterone acetate and cancer risk and compared these results with the oral contraceptive pill. We used conditional logistic regression to estimate odds ratios (OR) and 95% confidence intervals (CI).
J Colloid Interface Sci
January 2025
Department of Materials Science and Engineering, Shaanxi Province Key Laboratory of Corrosion and Protection, Xi'an University of Technology, Xi'an 710048 PR China.
Pitting corrosion caused by sulfate-reducing bacteria (SRB) significantly shortens the lifespan of metallic pipelines. Antibacterial coatings containing S-responsive drug-loaded nanocontainers represent a promising method to mitigate SRB corrosion. However, the challenge of balancing rapid bactericide release with continuous antibacterial effect limits their practical application.
View Article and Find Full Text PDFBMJ Sex Reprod Health
December 2024
Research Department of Reproductive Health, University College London (UCL) EGA Institute for Women's Health, London, UK.
PLoS One
January 2025
US Department of Veterans Affairs, Palo Alto Healthcare System, National Center for Collaborative Healthcare Innovation, Palo Alto, California, United States of America.
Background: The intrauterine device (IUD) is a highly effective form of long-acting reversible contraception, widely recognized for its convenience and efficacy. Despite its benefits, many patients report moderate to severe pain during and after their IUD insertion procedure. Furthermore, reports suggest significant variability in pain control medications, including no adequate pain medication.
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