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Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings. | LitMetric

Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings.

Int Health

Department of Gastroenterology and Hepatology, Erasmus MC, Wytemaweg 80, 3015 CE, Rotterdam, The Netherlands.

Published: July 2019

Background: Treatment of HCV with direct-acting antivirals has enabled the discussion of HCV eradication worldwide. Envisioning this aim requires implementation of mass screening in resource-limited areas, usually constrained by testing costs.

Methods: We validated a low-cost, rapid diagnosis test (RDT) for HCV in three different continents in 141 individuals.

Results: The HCV RDT showed 100% specificity and sensitivity across different samples regardless of genotype or viral load (in samples with such information, 90%).

Conclusions: The HCV test validated in this study can allow for HCV screening in areas of need when properly used.

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Source
http://dx.doi.org/10.1093/inthealth/ihy101DOI Listing

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