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First line treatment with subcutaneous efgartigimod in impending myasthenic crisis: a case report.
Ther Adv Neurol Disord
December 2024
Department of Neurology, Faculty of Medicine, University of Augsburg, Stenglinstrasse 2, Augsburg 86156, Germany.
In acetylcholine receptor (AChR) antibody-positive generalized myasthenia gravis (gMG), neonatal Fc-receptor (FcRn) inhibition has broadened the therapeutic spectrum. Myasthenic crisis (MC), heralded by an impending myasthenic crisis (iMC), is a critical condition requiring treatments with rapid onset and sustained efficacy. Currently treatments used for iMC, including intravenous immunoglobulins and plasma exchange/immunoadsorption, have limitations, such as delayed onset of action and potential side effects.
View Article and Find Full Text PDFDelayed Onset Iliopsoas Tendonitis With Intramuscular Hematoma Following Total Hip Arthroplasty.
Arthroplast Today
December 2024
Department of Orthopaedics, University of Miami Hospital, Miami, FL, USA.
Iliopsoas tendonitis following total hip arthroplasty (THA) can be challenging to diagnose due to the many causes of postoperative groin pain. This case involves a 66-year-old female with right-sided hip and groin pain and a palpable mass, 3 years post-THA. Initial recovery was unremarkable until the sudden onset of symptoms after exercise.
View Article and Find Full Text PDFDelayed-Onset White Matter Lesions on Brain MRI in Recurrent Non-cerebral Plasmodium falciparum Imported Malaria Without Neurological Symptoms.
Cureus
December 2024
Neurology, Adventist Health White Memorial, Los Angeles, USA.
malaria affects millions of people in certain regions of the world, with neurological involvement and/or cerebral malaria as potential manifestations. Brain magnetic resonance imaging (MRI) abnormalities have been well-documented in cerebral malaria. However, MRI abnormalities in non-cerebral malaria, especially in neurologically asymptomatic patients, are not well understood and have been less frequently reported, especially in non-endemic regions.
View Article and Find Full Text PDFAtypical Presentation of Subcapsular Liver Hematoma With a Delayed Onset of Hemolysis, Elevated Liver Enzymes, Low Platelet Count (HELLP) Syndrome.
Cureus
November 2024
Radiology, Epsom and St Helier NHS Trust, London, GBR.
Subcapsular liver haematoma in pregnancy, a rare and life-threatening condition, is more commonly associated with severe preeclampsia and haemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome. The common presenting symptom of subcapsular haematoma is acute-onset upper abdominal pain in patients suffering from preeclampsia; shock is the presenting feature in severe cases of rupture. Here we have discussed a case of subcapsular haematoma associated with HELLP syndrome in a patient who responded to conservative management.
View Article and Find Full Text PDFDelayed-Onset Arterial Gas Embolism After Underwater Egress Training.
Aerosp Med Hum Perform
November 2024
Background: Arterial gas embolism (AGE) may occur while breathing compressed air and failing to exhale during ascent to compensate for gas expansion as pressure decreases. Trauma to the lungs from over-pressurization may result in air bubbles entering the pulmonary veins and subsequently the systemic circulation, causing obstructed blood flow and inflammatory cascades. AGEs are known to always manifest within 10 min of surfacing from depth.
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