Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4103/0028-3886.253630 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Prevalence of adults with stimulant misuse and/or stimulant use disorder in Massachusetts, USA, 2014-2021.
Addiction
December 2024
Massachusetts General Hospital, Biostatistics Center, Boston, MA, USA.
Background And Aims: Stimulant-involved overdose deaths are increasing throughout the United States. Because stimulant misuse (i.e.
View Article and Find Full Text PDF[Cause of death statistics-how to avoid misinterpretation of mortality data].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
December 2024
Institut für medizinische Informatik, Biometrie und Epidemiologie, Universitätsklinikum Essen, Hufelandstr. 55, 45147, Essen, Deutschland.
National mortality registers provide important data for monitoring population health. Analyses of cardiovascular mortality in particular-and especially mortality from coronary heart disease-are frequently the basis for conclusions about the quality of healthcare and prevention. To be able to interpret disease-specific mortality differences between countries and changes in mortality over time, it is necessary to know the basics of monocausal cause-of-death statistics and the associated limitations in comparative statements.
View Article and Find Full Text PDFParental experiences of using continuous glucose monitoring in their young children with early-stage type 1 diabetes: a qualitative interview study.
Front Clin Diabetes Healthc
November 2024
Children's Diabetes Centre, Telethon Kids Institute, The University of Western Australia, Perth, WA, Australia.
Article Synopsis
- - The study aimed to investigate parents' experiences with continuous glucose monitoring (CGM) for their young children who have early-stage type 1 diabetes enrolled in the ENDIA study.
- - A total of nine parents participated in semi-structured phone interviews after a CGM monitoring period, highlighting three key themes: empowerment through information, acceptance of CGM use, and the benefits of involvement in research.
- - Results showed that parents had a positive experience with their children's use of CGM, feeling supported and less uncertain about managing their child's diabetes with the valuable data provided by the monitoring.
Real-time adaptive randomization of clinical trials.
J Clin Epidemiol
November 2024
Massachusetts Institute of Technology (MIT), MIT Sloan School of Management, Cambridge, USA.
Objectives: To evaluate real-time (day-to-day) adaptation of randomized controlled trials (RCTs) with delayed endpoints - a "forward-looking optimal-experimentation" form of response-adaptive randomization. To identify the implied tradeoffs between lowered mortality, CIs, statistical power, potential arm misidentification, and endpoint rate change during the trial.
Study Design And Setting: Using data from RCTs in acute myocardial infarction (30,732 patients in the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries, GUSTO-1) and coronary heart disease (12,218 patients in the EURopean trial On reduction of cardiac events with Perindopril in stable coronary Artery disease, EUROPA), we resample treatment-arm assignments and expected endpoints to simulate (1) real-time assignment, (2) forward-looking assignments adapted after observing a fixed number of patients ("blocks"), and (3) a variant that balances RCT and real-time assignments.
A general kernel machine regression framework using principal component analysis for jointly testing main and interaction effects: Applications to human microbiome studies.
NAR Genom Bioinform
September 2024
Department of Applied Mathematics and Statistics, The State University of New York, Korea, Incheon 21985, South Korea.
The effect of a treatment on a health or disease response can be modified by genetic or microbial variants. It is the matter of interaction effects between genetic or microbial variants and a treatment. To powerfully discover genetic or microbial biomarkers, it is crucial to incorporate such interaction effects in addition to the main effects.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!