AI Article Synopsis

  • Laugier-Hunziker syndrome is a rare, non-cancerous condition leading to dark pigmentation on the lips and inner cheeks, sometimes affecting the nails as well.
  • The exact cause is unclear, but it is believed that an increase in the enzyme responsible for melanin production, potentially triggered by tyrosine, plays a role.
  • A case study highlights a 66-year-old woman who has been diagnosed with this syndrome along with rheumatoid arthritis.

Article Abstract

Laugier-Hunziker syndrome is a rare benign idiopathic condition characterized by acquired macular pigmentation of the lips and buccal mucosa, often accompanied by melanonychia. Although the etiopathogenesis is not fully known, tyrosine is thought to be responsible for the pathogenesis of enzyme hyperactivity in melanin biosynthesis. We present the case of a 66-year-old woman diagnosed with Laugier-Hunziker syndrome and rheumatoid arthritis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409823PMC
http://dx.doi.org/10.5114/reum.2019.83243DOI Listing

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