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Examining the progress and implementation of neonatal peritoneal dialysis in the Ningxia autonomous region.
BMC Pediatr
January 2025
Department of Neonatology, PKUFH-NINGXIA Women & Children's Hospital, No.127 Lakeside Road, Jinfeng District, Yinchuan, Ningxia, 750001, China.
Background: Neonates are prone to experiencing acute kidney injury (AKI) and metabolic irregularities. Although hemodialysis is a primary treatment for these conditions, its utilization is not prevalent in the Ningxia Autonomous Region in China. Peritoneal dialysis (PD) presents itself as an alternative with benefits such as simplicity, cost-effectiveness, and minimal technical complexity compared to hemodialysis.
View Article and Find Full Text PDFAcute Fetal Metabolomic Changes in Twins Undergoing Fetoscopic Surgery for Twin-Twin Transfusion Syndrome.
Twin Res Hum Genet
February 2024
Cincinnati Children's Fetal Care Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, Ohio, USA.
Article Synopsis
- Fetuses experience major surgical stress and metabolic changes during fetoscopic surgery for twin-twin transfusion syndrome (TTTS), but the precise acute metabolic shifts are not well understood.
- A study evaluated amniotic fluid samples before and after surgery from four TTTS cases, revealing significant decreases in glucose and amino acids, while lactate levels increased.
- The findings suggest heightened catabolism in the recipient twin during surgery, prompting considerations for improving maternal and fetal nutrition to enhance outcomes during these procedures.
Fetal anemia in monochorionic twins: a review on diagnosis, management, and outcome.
Expert Rev Hematol
January 2023
Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands.
Introduction: Monochorionic twins may develop fetal anemia when blood is unequally distributed via the placental vascular anastomoses. This review focuses on the causes of fetal anemia in complicated monochorionic twins and highlights the differences in management and outcome.
Areas Covered: Fetal anemia can occur in the context of twin anemia polycythemia sequence (TAPS), chronic twin-twin transfusion syndrome (TTTS) and acute peripartum TTTS, and in cotwins after single fetal demise.
Monochorionic monoamniotic twin pregnancies.
Best Pract Res Clin Obstet Gynaecol
November 2022
Fetal Medicine Unit, Liverpool Women's Hospital, Liverpool, UK; Fetal Medicine Unit, St George's Hospital, London, UK; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, London, UK; Twins Trust Centre for Research and Clinical Excellence, St George's Hospital, London, UK. Electronic address:
Monochorionic monoamniotic (MCMA) twin pregnancy is rare and associated with increased complication rates when compared with singletons, dichorionic and monochorionic diamniotic pregnancy in general. Monoamnionicity presents an enormous challenge following its accurate diagnosis, where the absence of an inter-twin membrane subsequently results in cord entanglement and consistently fluctuating foetal position. Furthermore, the detection of twin-twin transfusion syndrome (TTTS) in MCMA pregnancy can be challenging in the absence of amniotic fluid volume discordance without the presence of the inter-twin dividing membrane.
View Article and Find Full Text PDFLong-term follow-up of complicated monochorionic twin pregnancies: Focus on neurodevelopment.
Best Pract Res Clin Obstet Gynaecol
November 2022
Willem-Alexander Children's Hospital, Department of Pediatrics, Division of Pediatric Psychology, Leiden University Medical Center, Leiden, the Netherlands.
Monochorionic twin pregnancies have an increased risk of morbidity and mortality. Due to the advancements in screening and treatment strategies, mortality rates have decreased. Improving survival rates demands a shift in scope toward long-term outcomes.
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