Acute kidney injury (AKI) is a frequent and wide complication of antibiotics therapy. In the present review article, we assessed the epidemiology, pathogenesis, risk factors, and clinical manifestation of antibiotic-induced AKI. The risk factors for the occurrence of antibiotic-induced AKI include medical comorbidities, coexisting drug therapies and the dosage, and therapeutic period of antibiotics. The prognosis of antibiotic-induced AKI varies by antibiotics types. This review summarizes the clinical controversy of antibiotic treatment and the future clinical recommendations.

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