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FOXO3, a Molecular Search for the Fountain of Youth. | LitMetric
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FOXO3, a Molecular Search for the Fountain of Youth.

Willem E Fibbe Yufang Shi

Cell Stem Cell

The First Affiliated Hospital of Soochow University, State Key Laboratory of Radiation Medicine and Protection, Institutes for Translational Medicine, Soochow University Medical College, Suzhou, Jiangsu 215123, China. Electronic address:

Published: March 2019

FOXO3 has been consistently associated with longevity and with a reduction in the prevalence of cardiovascular disease. In this issue, Yan et al. (2019) report that FOXO3-activated vascular cells derived from human embryonic stem cells (ESCs) promote multiple vascular functions and reverse cellular aging through the transcriptional repression of CSRP1.

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 Source
http://dx.doi.org/10.1016/j.stem.2019.02.008DOI Listing

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