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Intracameral voriconazole for severe fungal keratitis: a case series.
Arq Bras Oftalmol
January 2025
Department of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Purpose: This study aimed to report the use, efficacy, and safety of intracameral voriconazole as an adjuvant treatment for deep fungal keratitis.
Methods: This was a prospective case series of seven eyes with fungal keratitis with anterior chamber involvement or a corneal ulcer refractory to conventional topical treatment. In addition to topical treatment with 0.
[Investigation of the Antifungal Susceptibility and Virulence Factors of Fusarium Strains Isolated from Clinical Samples].
Mikrobiyol Bul
January 2025
Aydın Adnan Menderes Üniversitesi Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Aydın.
Fusarium türleri, insanlarda keratit ve onikomikoz başta olmak üzere invaziv veya invaziv olmayan çeşitli enfeksiyonlarda etken olan küf mantarlarıdır. Taksonomide Fusarium cinsi, tür kompleks [species complex (SC)]'lere ayrılmış, SC'ler de türlere ayrılmıştır. SC/tür düzeyinde identifikasyonun, morfolojik özelliklere göre yapılmasının güçlüğü nedeniyle moleküler yöntemlerin kullanımı önerilmektedir.
View Article and Find Full Text PDFRetraction Note: Establishment of an Acanthamoeba keratitis mouse model confirmed by amoebic DNA amplification.
Sci Rep
January 2025
Department of Microbiology, Ajou University School of Medicine, Suwon, 16499, Republic of Korea.
Phaeoisaria sp. fungal keratitis resembling corneal rust residue: a case report.
BMC Ophthalmol
January 2025
Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
Background: Fungal keratitis can develop after plant injury or after prolonged glucocorticoid use. Typical manifestations include corneal infiltrates, satellite lesions, plaques, and an immune ring. Some cases exhibit atypical signs, requiring reliance on etiological examination.
View Article and Find Full Text PDFPCR-based diagnosis and clinical insights into parasitic keratitis.
J Microbiol Immunol Infect
January 2025
Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:
Purpose: This retrospective study aimed to investigate demographic characteristics, predisposing factors, and clinical outcomes in patients with parasitic keratitis.
Methods: Medical records of patients with molecularly confirmed Acanthamoeba or microsporidia, identified through corneal scraping specimens (collected between September 21, 2017, and June 27, 2023), were reviewed. Demographic data, clinical profiles, such as symptom duration before confirmed diagnosis, antiviral treatment pre-diagnosis, contact lens use, tap water and soil contamination, ocular trauma, and treatment regimens, were analyzed.
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