AI Article Synopsis
- Limited data exists on noninvasive ventilation (NIV) in ICUs in South Korea, prompting a study in 20 university-affiliated hospitals from June 2017 to February 2018.
- A total of 156 patients underwent NIV, primarily for acute hypercapnic respiratory failure and post-extubation failure, using oronasal masks and mechanical ventilators.
- The overall NIV success rate was 68.5%, with higher success in patients with acute hypercapnic respiratory failure compared to those with respiratory failure, indicating factors like immune status and device type affected outcomes.
Article Abstract
Background: Data on noninvasive ventilation (NIV) use in intensive care units (ICUs) are very limited in South Korea.
Methods: A prospective observational study was performed in 20 ICUs of university-affiliated hospitals from June 2017 to February 2018. Adult patients (age>18 years) who were admitted to the ICU and received NIV treatment for acute respiratory failure were included.
Results: A total of 156 patients treated with NIV were enrolled (mean age, 71.9±11.6 years). The most common indications for NIV were acute hypercapnic respiratory failure (AHRF, n=89) and post-extubation respiratory failure (n=44). The main device for NIV was an invasive mechanical ventilator with an NIV module (61.5%), and the majority of patients (87.2%) used an oronasal mask. After the exclusion of 32 do-not-resuscitate patients, NIV success rate was 68.5% (85/124); ICU and hospital mortality rates were 8.9% and 15.3%, respectively. However, the success rate was lower in patients with respiratory failure (27.3%) compared to that of patients with AHRF (72.8%) or post-extubation respiratory failure (75.0%). In multivariate analysis, immunocompromised state, respiratory failure, post-NIV (2 hours) respiratory rate, NIV mode (i.e., non-pressure support ventilation mode), and the change of NIV device were significantly associated with a lower success rate of NIV.
Conclusion: AHRF and post-extubation respiratory failure were the most common indications for NIV in Korean ICUs. Overall NIV success was achieved in 68.5% of patients, with the lowest rate in patients with respiratory failure.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609522 | PMC |
| http://dx.doi.org/10.4046/trd.2018.0064 | DOI Listing |
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