Posterior reversible encephalopathy syndrome (PRES) is a completely reversible neuroradiological entity caused by accelerated hypertension, eclampsia, certain cytotoxic drugs and acute renal failure. PRES involves posterior circulation of the brain resulting in various manifestations, hence the name. Acute vision loss is one of the manifestations that occurs owing to the involvement of the visual pathway. However, loss of vision due to a lesion involving the lateral geniculate body alone is unusual. We report one such case of a young female who developed acute bilateral painless loss of vision without any other symptom during postpartum period. MRI brain showed features of PRES involving bilateral lateral geniculate body, hippocampus and brainstem. There was no involvement of retrogeniculate visual pathway, i.e. parieto-occipital cortex. The patient improved with optimal blood pressure control and was discharged after 5 days.
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http://dx.doi.org/10.4997/JRCPE.2019.107 | DOI Listing |
Brain Commun
December 2024
Division of Neurology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Following a unilateral post-chiasmal lesion of the geniculo-striate pathway, patients develop homonymous visual field defects. Using classical perimetry, patients with 'complete' homonymous hemianopia are unaware of stimuli in the affected hemifield. However, some show preserved vision in the affected hemifield in which the conscious perception of moving stimuli is preserved (Riddoch phenomenon).
View Article and Find Full Text PDFJ Clin Med
November 2024
Department of Orthopedic Surgery, Kanazawa Medical University, Kahoku 920-0293, Japan.
: Knee osteoarthritis (KOA) is a degenerative joint disease typically managed with conservative treatments, such as anti-inflammatory medications and intra-articular hyaluronic acid injections; however, advanced cases may eventually require surgical intervention. Recently, cooled radiofrequency ablation (CRFA) has emerged as a novel treatment option for alleviating KOA-related pain by temporarily disabling pain-transmitting nerves. This study evaluated the short-term effects of CRFA on pain relief and walking ability in KOA patients, with a specific focus on functional improvements in walking capacity.
View Article and Find Full Text PDFPLoS Comput Biol
December 2024
Department of Physics, Norwegian University of Life Sciences, Ås, Norway.
The local field potential (LFP), the low-frequency part of the extracellular potential, reflects transmembrane currents in the vicinity of the recording electrode. Thought mainly to stem from currents caused by synaptic input, it provides information about neural activity complementary to that of spikes, the output of neurons. However, the many neural sources contributing to the LFP, and likewise the derived current source density (CSD), can often make it challenging to interpret.
View Article and Find Full Text PDFCurr Biol
December 2024
Department of Biological Sciences, Purdue Institute for Integrative Neuroscience, Purdue University, 915 Mitch Daniels Blvd., West Lafayette, IN 47907, USA. Electronic address:
Visual experience gives rise to persistent theta oscillations in the mouse primary visual cortex (V1) that are specific to the familiar stimulus. Our recent work demonstrated the presence of these oscillations in higher visual areas (HVAs), where they are synchronized with V1 in a context-dependent manner. However, it remains unclear where these unique oscillatory dynamics originate.
View Article and Find Full Text PDFCurr Biol
November 2024
Deptartment of Psychological Sciences, University of Connecticut, Storrs, CT 06269, USA. Electronic address:
Motion perception is crucial to animal survival and effective environmental interactions. In mammals, detection of movement begins in the retina. Directionally selective (DS) retinal ganglion cells were first discovered in the rabbit eye, and they have since been found in mouse, cat, and monkey.
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