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Phenotypic characterization and quality of life of Labradoodles with idiopathic epilepsy and epilepsy of unknown cause.
Front Vet Sci
October 2024
Expertise Centre of Genetics, Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Article Synopsis
- Idiopathic epilepsy (IE) is a chronic neurological disorder affecting Labradoodles, with a specific focus on characterization including age of onset, seizure frequency, and impact on quality of life for both dog and owner.
- An online survey involving Labradoodle owners revealed that 33 out of 40 dogs either had IE or were suspected of having it, with an average age of onset at 2.3 years and an average seizure frequency of 5.4 seizures per year; stress was the most common trigger for seizures.
- Despite some dogs experiencing severe forms of epilepsy, such as cluster seizures and status epilepticus, a majority managed well with minimal treatment, reflecting high quality of life scores for both the dogs
Feasibility of in-home electroencephalographic and actigraphy recordings in dogs.
Front Vet Sci
January 2024
Department of Clinical Studies, University of Guelph, Guelph, ON, Canada.
Introduction: Idiopathic epilepsy is a prevalent neurological disease in dogs. Dogs with epilepsy often present with behavioral comorbidities such as aggression, anxiety, and fear. These behaviors are consistent with pre, post, or interictal behaviors, prodromal changes, seizure-precipitating factors, or absence and focal seizures.
View Article and Find Full Text PDFTools and techniques for classifying behaviours in canine epilepsy.
Front Vet Sci
November 2023
Department of Clinical Studies, University of Guelph, Guelph, ON, Canada.
Idiopathic epilepsy is the most common neurological disease in dogs. Similar to humans, dogs with epilepsy often experience behavioural comorbidities such as increased fear, anxiety, and aggression, as reported by their caregivers. Investigations of behaviour in canine epilepsy have yet to untangle interictal and pre and postictal behaviours, prodromal changes, and seizure-precipitating factors.
View Article and Find Full Text PDFRemarkable anecdotes illustrating the nature and effect of seizure-precipitating factors in Border Collies with idiopathic epilepsy.
Front Vet Sci
September 2023
Evidensia Referral Hospital Arnhem, Arnhem, Netherlands.
Epilepsy is one of the most common chronic neurological syndromes in dogs and has serious implications for the quality of life of both the dogs and owners. Seizure-precipitating factors (SPFs) (also termed "triggers" or "provocative factors") have been studied and reported in both humans and dogs with idiopathic epilepsy. In dogs stress, hormones, sleep deprivation, and the weather have been reported as SPFs.
View Article and Find Full Text PDFStress biomarkers in adult patients with drug-resistant epilepsy on a modified Atkins diet: A prospective study.
Epilepsia Open
December 2023
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Objective: Ketogenic diets like the modified Atkins diet (MAD) are increasingly used in patients with refractory epilepsy. For epilepsy patients, stress is a well-known seizure-precipitating factor. New possibilities for measuring biomarkers of stress are now available.
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