[An Improved Method for Electroencephalographic Detection of Epileptic Discharge].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao

National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences,CAMS and PUMC,Beijing 100005,China.

Published: February 2019

Objective To investigate the role of OpenBCI module in the electroencephalographic (EEG) detection of epileptic discharge.Methods C57BL/6J mice aged 8-12 weeks were divided into two groups:the sham-operated group and kainic acid-induced epileptic group. Spontaneous seizures were monitored continuously for 3 weeks either by EEG or by OpenBCI.Results Up to 8 mice could be simultaneously monitored by OpenBCI. Meanwhile,the module accurately recorded the resting discharge,EEG spikes,and seizures.Conclusion Compared with the conventional brain function monitoring system,the OpenBCI module has lower cost and data occupancy and thus may be applied in clinical settings.

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http://dx.doi.org/10.3881/j.issn.1000-503X.10418DOI Listing

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