A chemical investigation of (Maxim.) Kom. identified 8 compounds. On the basis of spectroscopic data, they were determined to be 3 alkaloids and 5 sinapoyl esters, among which were two previously undescribed compounds ( and ). The inhibitory effects of the isolated compounds against four human tumor cell lines were evaluated in vitro by MTT assays, which revealed moderate inhibitory effects with IC values < 50 mM, in particularly, three antofine analogues have showed significant antitumor activities with IC values < 0.1 mM, which was obviously better than the 5-fluorouracil and potential to be used as cancer drugs.
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