AI Article Synopsis
- Leiomyosarcoma (LMS) is a rare smooth muscle tumor, making up about 11% of soft-tissue sarcomas, and can occur in various body locations, most frequently in the uterus and gastrointestinal tract.
- There is limited documentation on LMS spreading to skeletal muscle, highlighting the rarity of such cases.
- The report discusses a unique case of metastatic LMS in a 71-year-old male's forearm, emphasizing the challenges in diagnosing and managing this unpredictable tumor.
Article Abstract
Leiomyosarcoma (LMS) is a rare smooth muscle connective tissue tumour accounting for around 11% of soft-tissue sarcomas (Ducimetiere F, Lurkin A, Ranchere-Vince D, Decouvelaere AV, Péoc'h M, Istier L . Incidence of sarcoma histotypes and molecular subtypes in a prospective epidemiological study with central pathology review and molecular testing. 2011;6:e20294). LMS are highly unpredictable tumours that can present at any site in the body, most commonly in the uterus, stomach, small intestine and retroperitoneum. There are few published case reports within the literature on the metastatic spread of LMS to skeletal muscle. We present an unusual presentation of metastatic Leiomyosarcoma in the right forearm of a 71-year-old male treated with limb-sparing surgical excision. This case report demonstrates the unusual and unpredictable nature of metastatic LMS presentation, which poses difficulty in diagnosis and management.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388081 | PMC |
| http://dx.doi.org/10.1093/jscr/rjy350 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The B Chromosome of Pseudococcus viburni: A Selfish Chromosome that Exploits Whole-Genome Meiotic Drive.
Genome Biol Evol
January 2025
School of Biological Sciences, Institute of Ecology and Evolution, The University of Edinburgh, Edinburgh EH9 3FL, UK.
Meiosis is generally a fair process: each chromosome has a 50% chance of being included into each gamete. However, meiosis can become aberrant with some chromosomes having a higher chance of making it into gametes than others. Yet, why and how such systems evolve remains unclear.
View Article and Find Full Text PDFA rare case of culture-negative infective endocarditis following cataract surgery.
J Int Med Res
January 2025
Colombo South Teaching Hospital, Colombo, Sri Lanka.
A 70-year-old man developed intermittent fever with chills, severe anorexia, generalized weakness, and mild exertional difficulty in breathing following posterior chamber intraocular lens replacement surgery for a mature white cataract in the left eye. Laboratory tests revealed persistent negative blood cultures, normocytic and normochromic anemia, neutrophilia, and elevated inflammatory markers despite multiple courses of antibiotics. All other investigations conducted to identify the cause of prolonged fever, including transthoracic echocardiography, were negative.
View Article and Find Full Text PDFResonant song recognition and the evolution of acoustic communication in crickets.
iScience
February 2025
ENI-G, a Joint Initiative of the University Medical Center Göttingen and the Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Cricket song recognition is thought to evolve through modifications of a shared neural network. However, the species has an unusual recognition pattern that challenges this view: females respond to both normal male song pulse periods and periods twice as long. Of the three minimal models tested, only a single-neuron model with an oscillating membrane could explain this unusual behavior.
View Article and Find Full Text PDFJAK2 V617F Mutation Leading to Portal Vein Thrombosis in a Young Patient: A Case Report.
Cureus
December 2024
Radiodiagnosis, Malla Reddy Medical College for Women, Hyderabad, IND.
Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders commonly characterized by excessive production of blood cell lineages. The JAK2 V617F mutation plays a crucial role in the pathogenesis of these conditions, often leading to thrombotic complications. Here, we present the case of a 21-year-old man who presented with acute abdominal pain and was found to have portal vein thrombosis with splenomegaly.
View Article and Find Full Text PDFRare Presentation of Cutaneous Metastasis in Breast Carcinoma.
Cureus
December 2024
Surgery, All India Institute of Medical Sciences, New Delhi, IND.
Recurrence beyond the second year of diagnosis and metastasis to the skin and eyelids are rare occurrences in breast cancer. When cutaneous metastases present without local recurrence, they pose a significant diagnostic challenge. Here, we describe a case of breast cancer that recurred 16 years after the initial treatment, with the only indication of recurrence being unusual skin and eyelid lesions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!