A laboratory scale ultrasonic flow reactor capable of enhancing enzymatic reactions has been built and characterized using as a model reaction the enzymatic synthesis of isoamyl acetate using Lipozyme 435 immobilized on a macroporous anion exchange resin. The efficiency of the reactor was determined in relation to ultrasonic power density (measured by 4-nitrophenol dosimetry), position of ultrasonic horn and temperature. The results show that ultrasound can enhance the process efficiency and also reduce the reaction time.
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