Objective: The evaluation of the hypolipidemic and antioxidant activities of the aerial parts aqueous extract of (APAE of C. telephiifolia) in normal and streptozotocin (STZ)-induced diabetic rats.
Methods: The effects of oral administration of APAE of C. telephiifolia (5 mg/kg) on the lipid profile as well as the in vitro antioxidant activity of this aqueous extract have been determined.
Results: APAE of C. telephiifolia (5 mg/kg) reduced significantly (p<0.001) the plasma total cholesterol levels in diabetic rats. In contrast, no significant increase in plasma triglyceride levels in normal and in STZ-induced diabetic rats was observed. On the other hand, APAE of C. telephiifolia showed an antioxidant activity.
Conclusion: The APAE of C. telephiifolia exhibits an antioxidant, cholesterol and body weightlowering activities in diabetic rats.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875864 | PMC |
http://dx.doi.org/10.2174/1871525717666190227231834 | DOI Listing |
Cardiovasc Hematol Agents Med Chem
November 2019
Faculty of Sciences and Techniques Errachidia, Moulay Ismail University, BP 509, Boutalamine, 52000, Errachidia, Morocco.
Objective: The evaluation of the hypolipidemic and antioxidant activities of the aerial parts aqueous extract of (APAE of C. telephiifolia) in normal and streptozotocin (STZ)-induced diabetic rats.
Methods: The effects of oral administration of APAE of C.
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