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T-cell mitochondrial dysfunction and lymphopenia in DOCK2-deficient patients. | LitMetric
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T-cell mitochondrial dysfunction and lymphopenia in DOCK2-deficient patients.

Mohammed F Alosaimi Hiba Shendi Abdallah Beano Kelsey Stafstrom Rabab El Hawary Safa Meshaal Nermeen Galal Sung-Yun Pai Aisha El-Marsafy Raif S Geha Janet Chou

J Allergy Clin Immunol

Division of Immunology, Boston Children's Hospital and Harvard Medical School, Boston, Mass. Electronic address:

Published: July 2019

This study delineates the mitochondrial defects in DOCK2-deficient T cells contributing to the T cell lymphopenia characteristic of this primary immunodeficiency.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612298PMC
http://dx.doi.org/10.1016/j.jaci.2019.02.020DOI Listing

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