AI Article Synopsis
- The study investigates how changes in the structure of the hippocampus relate to cognitive performance and symptoms in adolescents with schizophrenia, focusing on language memory.
- It finds that the left hippocampal volume in schizophrenic patients is significantly lower than in healthy individuals when adjusted for overall brain size.
- Additionally, the research highlights that the left hippocampus mediates the relationship between negative symptoms of schizophrenia and speech memory, indicating its crucial role in the disorder's development.
Article Abstract
In order to explore the relationship between hippocampal structure changes and performance symptoms as well as cognitive function in adolescent schizophrenia, taking the brain response signals of psychiatric patients as the research object, the relationship between hippocampal volume drawn by schizophrenia and language memory of negative symptoms is explored based on morphological analysis method. It is found that the left hippocampal volume of schizophrenic patients is abnormal when the whole brain volume is returned, which is significantly lower than that of normal people. It is also found that the left hippocampus volume of schizophrenic patients is a mediator between negative symptoms and speech memory. The results show that the left hippocampus of schizophrenic patients plays an important role in the pathogenesis of schizophrenia.
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| http://dx.doi.org/10.1007/s10916-019-1213-9 | DOI Listing |
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