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http://dx.doi.org/10.1038/s12276-019-0224-4 | DOI Listing |
Aquat Toxicol
December 2024
College of Fisheries, Guangdong Ocean University, Zhanjiang, 524088, China; Guangdong Provincial Shrimp Breeding and Culture Laboratory, Guangdong Ocean University, Zhanjiang, 524088, China. Electronic address:
The toxic effects of ammonia exposure on Litopenaeus vannamei have been widely reported, including tissue damage, oxidative stress, and metabolic disorders, but the ability of L. vannamei to recover from ammonia damage is still unclear. To further understand the adaptation mechanism of L.
View Article and Find Full Text PDFInt J Biol Macromol
November 2024
Stomatology Center of Jingyue Campus, The First Hospital of Jilin University, Jilin University, Changchun 130021, China; Scientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin University, Changchun 130021, China; Jilin Provincial Engineering Laboratory of Bone Regeneration and Tissue Repair Materials, Jilin University, Changchun 130021, China; Jilin Provincial Joint University-Industry Innovation Laboratory for Oral Biomedical Materials, Jilin University, Changchun 130021, China. Electronic address:
Bacterial infection, reactive oxygen species (ROS) accumulation, and persistent inflammation pose significant challenges in the treatment of periodontitis. However, the current single-modal strategy makes achieving the best treatment effect difficult. Herein, we developed a double-network hydrogel composed of Pluronic F127 (PF-127) and hyaluronic acid methacrylate (HAMA) loaded with spermidine-modified mesoporous polydopamine nanoparticles (M@S NPs).
View Article and Find Full Text PDFAging Cell
October 2024
Institute of Molecular Medicine, Ulm University, Ulm, Germany.
Aged hematopoietic stem cells (HSCs) show reduced reconstitution potential, limiting their use in transplantation settings in the clinic. We demonstrate here that exposure of aged HSCs ex vivo to a pH of 6.9 instead of the commonly used pH of 7.
View Article and Find Full Text PDFMol Plant Pathol
September 2024
Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Plant Protection, South China Agricultural University, Guangzhou, China.
Sugarcane smut fungus Sporisorium scitamineum produces polyamines putrescine (PUT), spermidine (SPD), and spermine (SPM) to regulate sexual mating/filamentous growth critical for pathogenicity. Besides de novo biosynthesis, intracellular levels of polyamines could also be modulated by oxidation. In this study, we identified two annotated polyamine oxidation enzymes (SsPAO and SsCuAO1) in S.
View Article and Find Full Text PDFBenef Microbes
August 2024
Precision Nutrition and Cardiometabolic Health, IMDEA-Alimentacion Institute (Madrid Institute for Advanced Studies), Campus of International Excellence (CEI), UAM + CSIC, 28049 Madrid, Spain.
The consumption of a high-fat high-fructose diet partly resemble the western dietary patterns, which is closely associated with excessive body adiposity and metabolic disorders, such as obesity and type 2 diabetes. Moreover, this unhealthy regime produces unfavourable changes on the faecal microbiota, potentially interfering with microorganisms postbiotic function, such as spermidine, a natural polyamine that has been involved in the control of weight gain. The study aimed to analyse the repercussions of spermidine supplementation on somatic measurements, metabolic markers, and the faecal microbiota profile of rats fed a diet rich in fat and fructose.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!