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Article Synopsis
  • Uterine leiomyomas can sometimes lead to serious conditions like deep vein thrombosis (DVT) and pulmonary embolism (PE), even in patients with no known risk factors.
  • A 38-year-old woman experienced leg swelling, pain, and breathing difficulties and was diagnosed with DVT and PE, which were confirmed through imaging.
  • The treatment involved mechanical thrombectomy and hysterectomy, resulting in a full recovery with no recurrence of thromboembolic events after 11 months.
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This article presents the case of a 52-year-old male who arrived at the emergency department with escalating chest pain and shortness of breath. An urgent CT scan revealed a right pulmonary embolism and inferior vena cava thrombus, prompting immediate anticoagulant therapy. Further diagnostic evaluations confirmed nephrotic syndrome (NS).

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Background: While direct oral anticoagulants (DOACs) have improved oral anticoagulation management, inappropriate prescribing remains prevalent and leads to adverse drug events. Antithrombotic stewardship programs seek to enhance DOAC prescribing but require scalable and sustainable strategies.

Objective: We present a pilot, prescriber-level randomized controlled trial to assess the effectiveness of electronic health record (EHR)-based medication alerts in a large health system.

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Article Synopsis
  • Managing limb ischemia in cancer patients with complex histories of surgery and radiation is difficult due to complications like radiation arteritis and extensive tissue scarring.
  • A 68-year-old male with a history of liposarcoma developed severe limb ischemia, and traditional endovascular treatment failed, leading to a bypass surgery from the axillary to the popliteal artery.
  • Post-surgery, the patient had reduced pain and regained some mobility, but continued rehabilitation was needed due to persistent foot drop.
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Background: Kyphoplasty-associated cement extravasation into surrounding tissue and vasculature can lead to life-threatening complications. We present a rare case of significant inferior vena cava cement burden that resulted in pulmonary embolism.

Case Presentation: A 74-year-old Caucasian woman with a history of severe osteoporosis, recurrent falls, and spinal compression fracture status post-kyphoplasty of the L4-L5 vertebrae, presents to the emergency department 2 days post-vertebral kyphoplasty due to chest pain, back pain, and dyspnea.

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