Plasma nitriding under low temperature improves the endothelial cell biocompatibility of 316L stainless steel.

Biotechnol Lett

Departamento de Ciências Animais, Universidade Federal Rural do Semi-Árido, UFERSA, Av. Francisco Mota, 572 -Bairro Costa e Silva, Mossoró, RN, CEP: 59.625-900, Brazil.

Published: May 2019

AI Article Synopsis

  • The study aimed to assess how low-temperature plasma nitriding affects endothelial cells on 316L stainless steel to enhance its application in stents.
  • XRD analysis showed nitrogen incorporation into the steel, resulting in increased surface roughness and hydrophilicity, which promoted better cell adhesion and viability.
  • Overall, the nitriding treatment improved the biocompatibility of stainless steel, making it a better candidate for stent manufacturing.

Article Abstract

Objectives: To evaluate the effects of the surface modification of 316L stainless steel (SS) by low-temperature plasma nitriding on endothelial cells for stent applications.

Results: X-ray diffraction (XRD) confirmed the incorporation of nitrogen into the treated steel. The surface treatment significantly increased SS roughness and hydrophilic characteristics. After 4 h the cells adhered to the nitride surfaces and formed clusters. During the 24 h incubation period, cell viability on the nitrided surface was higher compared to the polished surface. Nitriding reduced late apoptosis of rabbit aorta endothelial cell (RAEC) on the SS surface.

Conclusion: Low temperature plasma nitriding improved the biocompatible of stainless steel for use in stents.

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Source
http://dx.doi.org/10.1007/s10529-019-02657-7DOI Listing

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