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http://dx.doi.org/10.1371/journal.ppat.1007548 | DOI Listing |
J Mater Chem B
January 2025
College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China.
Circulating histones have been identified as essential mediators that lead to hyperinflammation, platelet aggregation, coagulation cascade activation, endothelial cell injury, multiple organ dysfunction, and death in severe patients with sepsis, multiple trauma, COVID-19, acute liver failure, and pancreatitis. Clinical evidence suggests that plasma levels of circulating histones are positively associated with disease severity and survival in patients with such critical diseases. However, safe and efficient therapeutic strategies targeting circulating histones are lacking in current clinical practice.
View Article and Find Full Text PDFR Soc Open Sci
January 2025
Department of Biodiversity Studies and Bioeducation, University of Lodz, Faculty of Biology and Environmental Protection, Banacha 1/3, Lodz 90-237, Poland.
There is a growing body of evidence that urbanization can affect body condition and immune function in wild birds, although these effects may be complex and taxa-specific. Here, we assessed the effects of urbanization on body condition (size-corrected body mass and haemoglobin concentration) and innate immune defences (haemolysis-haemagglutination assay, haptoglobin concentration and bacterial killing assay) in 136 Eurasian coots () from three urban and three non-urban populations across Poland. We also quantified the heterophil to lymphocyte ratio to control for the potential effect of physiological stress on immune defences.
View Article and Find Full Text PDFAnimals (Basel)
December 2024
Molecular Biology Techniques Laboratory, Faculty of Biology, Adam Mickiewicz University in Poznań, Uniwersytetu Poznańskiego 6, 61-614 Poznań, Poland.
is a common intracellular bacterial genus that infects numerous arthropods and filarial nematodes. In arthropods, it typically acts as a reproductive parasite, leading to various phenotypic effects such as cytoplasmic incompatibility, parthenogenesis, feminization, or male-killing. Quill mites (Acariformes: Syringophilidae) are a group of bird parasites that have recently attracted increasing interest due to the detection of unique phylogenetic lineages of endosymbiotic bacteria and potentially pathogenic taxa.
View Article and Find Full Text PDFArch Razi Inst
June 2024
Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
Newcastle disease (ND) is among the most common and deadliest poultry diseases worldwide. Thermostable Newcastle disease virus (NDV) vaccines have been widely used to protect village chickens against ND due to their decreased dependence on cold chains for transport and storage. The NDV4 Heat-Resistant (NDV4HR) vaccine is an apathogenic, heat-resistant, live vaccine that can induce immunity in chickens.
View Article and Find Full Text PDFMicrob Pathog
February 2025
Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, Food Research Center, University of São Paulo, Brazil.
Salmonella enterica subsp. enterica serovar Havana is a potential pathogenic serotype that can cause human foodborne illness. Therefore, we have conducted a microbiological and genomic surveillance study of Salmonella Havana from food in Brazil.
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